A new systematic review and a 91-case series shed light on Aspergillus endophthalmitis
A new systematic review and a 91-case series shed light on Aspergillus endophthalmitisWed, 04/08/2020 - 14:13News blog
In this study, we determine whether the fluorescence labeling processes themselves influence the results of the phagocytosis measurements. Here, alveolar macrophages, which form one of the most important compartments of the innate immune system, were used as an example of host cells, whereas Aspergillus fumigatus and Lichtheimia corymbifera that cause aspergillosis and mucormycosis, respectively, were studied as examples for pathogens. At first, our study investigated the importance of the sequence of steps of the fixation process when preparing the confrontation assay sample for microscopy studies. Here we showed that app...
Authors: Noguchi H, Matsumoto T, Kimura U, Hiruma M, Kano R, Yaguchi T, Ihn H Abstract The incidence of non-dermatophyte mould onychomycosis has been increasing worldwide for the past several decades, but it is not well recognized in Japan. Recent molecular techniques and phylogenetic analyses contributed to the identification of uncommon and emerging species. We came across 13 (0.5%) cases of non-dermatophyte onychomycosis among a total of 2,591 onychomycosis cases in 106,703 outpatients during the past 5 years (January 2015-December 2019). The cases included 5 patients with Aspergillus species, 4 patients with Fu...
Journal of Natural ProductsDOI: 10.1021/acs.jnatprod.0c00189
This study revealed the dynamic nature of the interaction between the two organisms.
In conclusion, a favorable performance of the Bruker MALDI-TOF MS in identification of clinical non-Aspergillus isolates directly inoculated on solid agar media could be achieved with the adoption of alternative interpretation criteria. Antifungal susceptibility testing is important for non-Aspergillus molds, especially when information on triazole susceptibility is required, and the Sensititre YeastOne is a practical and reliable method to determine antifungal susceptibilities of non-Aspergillus molds.
AbstractInfluenza was recently reported as a risk factor for invasive aspergillosis (IA). We aimed to describe prognostic factors for influenza-associated IA (IAA) and poor outcome and mortality in critically ill patients in Switzerland. All adults with confirmed influenza admitted to the ICU at two Swiss tertiary care centres during the 2017/2018 influenza season were retrospectively evaluated. IAA was defined by clinical, mycological and radiological criteria: a positive galactomannan in bronchoalveolar lavage or histopathological or cultural evidence in respiratory specimens ofAspergillus spp., any radiological infiltra...
CONCLUSION: Although uncommon, we must consider Aspergillus as the causative organism in apparently immunocompetent patients with history of recent systemic corticosteroids treatment, especially if they suffer a broncopulmonary disorder. Aspergillus is an aggressive organism so a high index of suspicion along with early diagnosis and prompt treatment is the key for better outcomes. We highlight A. nidulans as the causative agent as there are no other reported cases. PMID: 32486857 [PubMed - as supplied by publisher]
Publication date: Available online 1 June 2020Source: Journal de Mycologie MédicaleAuthor(s): Abdolreza Mohamadnia, Zahra Salehi, Zahra Namvar, Payam Tabarsi, Mihan Pourabdollah Toutkaboni, Sassan Rezaie, Majid Marjani, Afshin Moniri, Zahra Abtahian, Syed Ali Reza Mahdaviani, Vida mortezaee, Elham Askari, Somayeh Sharifynia
Publication date: Available online 8 May 2020Source: Journal de Mycologie MédicaleAuthor(s): R. Erfandoust, R. Habibipour, J. Soltani
Publication date: Available online 30 May 2020Source: Fungal BiologyAuthor(s): Esther GARCIA-CELA, Carol VERHEECKE-VAESSEN, Maria GUTIERREZ-POZO, Elisavet KIAITSI, Alessandra MARCON-GASPERINI, Naresh MAGAN, Angel MEDINA