Loss of insulin signaling may contribute to atrial fibrillation and atrial electrical remodeling in type 1 diabetes [Medical Sciences]

This study investigated AF susceptibility and atrial electrophysiology in type 1 diabetic Akita mice using in vivo intracardiac electrophysiology, high-resolution optical mapping in atrial preparations, and patch clamping in isolated atrial myocytes. qPCR and...

Source: Proceedings of the National Academy of Sciences - April 6, 2020 Category: Science Authors: Iuliia Polina, Hailey J. Jansen, Tiesong Li, Motahareh Moghtadaei, Loryn J. Bohne, Yingjie Liu, Pooja Krishnaswamy, Emmanuel E. Egom, Darrell D. Belke, Sara A. Rafferty, Martin Ezeani, Anne M. Gillis, Robert A. Rose Tags: Biological Sciences Source Type: research