IJERPH, Vol. 17, Pages 2534: The Preventive Effect of Lactoferrin-Containing Yogurt on Gastroenteritis in Nursery School Children —Intervention Study for 15 Weeks
IJERPH, Vol. 17, Pages 2534: The Preventive Effect of Lactoferrin-Containing Yogurt on Gastroenteritis in Nursery School Children—Intervention Study for 15 Weeks
International Journal of Environmental Research and Public Health doi: 10.3390/ijerph17072534
Authors:
Teruomi Tsukahara
Anri Fujimori
Yuka Misawa
Hirotsugu Oda
Koji Yamauchi
Fumiaki Abe
Tetsuo Nomiyama
To evaluate the effects of bovine lactoferrin (LF)-containing yogurt on gastroenteritis in nursery school children during the winter season, we conducted a randomized prospective study. A total of 1296 children were randomized into a group in which LF was provided in yogurt (LF group, n = 661) and a non-LF consumption group (control group, n = 635). The LF group was given LF-containing yogurt (100 mg/day) on all 5 weekdays for approximately 15 weeks, and the control group consumed fruit jelly instead of the yogurt. The final totals of 578 children as the LF group and 584 as the control group were analyzed. The total number of children who were absent from school due to vomiting was significantly lower in the LF group compared to the control, accounting for ≥3 days in any week: 10/234 (4.3%) vs. 49/584 (8.4%), respectively; p = 0.04. Regarding the relationship between absences due to vomiting and the consumption of the LF-containing yogurt, the adjusted odds ratio for absence due to vomiting was 2.48 (95% CI: 1.19–5.14) in the LF children who consumed LF-containing yogurt ...
Source: International Journal of Environmental Research and Public Health - Category: Environmental Health Authors: Teruomi Tsukahara Anri Fujimori Yuka Misawa Hirotsugu Oda Koji Yamauchi Fumiaki Abe Tetsuo Nomiyama Tags: Article Source Type: research
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