Hangover drug shows wider benefits in USC research

(University of Southern California) The hangover remedy DHM may have broader applications for substance abuse treatment and liver disease.
Source: EurekAlert! - Social and Behavioral Science - Category: International Medicine & Public Health Source Type: news

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Considering that female sexual hormones may modulate the inflammatory response and also exhibit direct effects on the cells of the immune system, herein, we intend to discuss the sex differences and the role of estradiol in modulating the lung and systemic inflammatory response, focusing on its possible application as a treatment modality for SARS-CoV-2 patients. COVID-19 patients develop severe hypoxemia early in the course of the disease, which is silent most of the time. Small fibrinous thrombi in pulmonary arterioles and a tumefaction of endothelial were observed in the autopsies of fatal COVID-19 cases. Studies showed...
Source: Clinics - Category: General Medicine Source Type: research
ConclusionsPatients who receive neoadjuvant chemotherapy for liver metastasis surgery have a greater splenic volume increase, which correlates with NAFLD and a lower survival.
Source: Clinical and Translational Oncology - Category: Cancer & Oncology Source Type: research
Brief Interventions (BIs) for problematic drug use in general medical settings, including in Emergency Departments (EDs), have shown disappointing results compared to those that target problematic alcohol use. Telephone booster calls may augment the impact of a BI delivered in the ED. The current study uses data from the National Drug Abuse Treatment Clinical Trials Network (CTN) Protocol 0047, “Screening, Motivational Assessment, Referral, and Treatment in Emergency Departments (SMART-ED)”, a multisite randomized clinical trial conducted in six EDs in the U.S.
Source: Journal of Substance Abuse Treatment - Category: Addiction Authors: Source Type: research
AbstractPurpose of ReviewThis review summarizes recent animal and human trials examining the potential for kefir to improve obesity, type 2 diabetes, dyslipidemia, and non-alcoholic fatty liver disease (NAFLD). Evidence for pathways affected and suggestions of possible mechanisms of action are also considered.Recent FindingsHuman trials examining the ability of kefir to recapitulate metabolic health benefits previously observed in rodent models have found mixed results.SummaryKefir has long been associated with improvements in health including obesity, diabetes, NAFLD, and dyslipidemia in preventative animal trials. While ...
Source: Current Nutrition Reports - Category: Nutrition Source Type: research
This study aim...
Source: SafetyLit - Category: International Medicine & Public Health Tags: Age: Adolescents Source Type: news
This study aimed to investigate the association between the degree of thoracic duct dilatation and the progression of chronic liver disease. In this cross-sectional and retrospective study, 179 patients (mean age, 60.9 years; 114 men) with chronic liver disease who underwent chest CT were enrolled. Dilatation of the left distal thoracic ducts (DTD) was measured and divided into the following 3 grades according to the maximum transverse diameter: grade 0, invisible thoracic duct; grade 1, visible duct with
Source: Medicine - Category: Internal Medicine Tags: Research Article: Observational Study Source Type: research
Cytokeratin 18 (CK18) and fibroblast growth factor 21 (FGF21) are elevated in patients with nonalcoholic fatty liver disease (NAFLD) and are useful markers for identifying or monitoring outcomes. Exercise therapy is one of the established treatments for NAFLD; however, few studies have investigated the effectiveness of exercise therapy on CK18 and FGF21 levels. Therefore, the aim of the present study was to assess the effects of 12 weeks of simple resistance exercise on CK18 and FGF21 levels in patients with NAFLD. Fifty patients with NAFLD were assigned to a resistance exercise group (n = 23) or a control group (n ...
Source: Medicine - Category: Internal Medicine Tags: Research Article: Observational Study Source Type: research
It is with great interest that I read the publication of F. Zingone et al. recommending screening for active coronavirus disease 2019 infection (CoVID-19) and immunization status prior to biologic therapy in inflammatory bowel disease (IBD) patients at the time of the pandemic outbreak [1]. As the authors suggest, the screening of CoVID-19 positive cases is mandatory in the management of IBD patients even when presenting symptoms are exclusively digestive. However, the screening should not be limited to swab or throat samples.
Source: Digestive and Liver Disease - Category: Gastroenterology Authors: Tags: Correspondence Source Type: research
To reduce the risk of overwhelming their healthcare systems during the COVID-19 pandemic, many countries are postponing medical services and procedures considered as “non-essential” or “deferrable”. However, this practice could eventually contribute to increasing the burden due to other medical conditions.
Source: Digestive and Liver Disease - Category: Gastroenterology Authors: Tags: Correspondence Source Type: research
While not everyone who binge drinks suffers from alcoholism, most people who suffer from alcoholism binge drink. This makes addiction the most dangerous side effect of binge drinking because it can cause devastating consequences; anything from a broken family to death can happen. Binge drinking is the practice of consuming large quantities of alcohol in a single session, usually defined as five or more drinks at one time for a man, or four or more drinks at one time for a woman. If you or a loved one binge drinks and think it is harmless fun, it is time to rethink binge drinking as an extremely dangerous and possibly fata...
Source: Cliffside Malibu - Category: Addiction Authors: Tags: Alcohol Alcohol Rehab Information Alcoholism Drinking alcohol abuse alcohol treatment binge binge drinking Source Type: blogs
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