Candida tropicalis is the most prevalent yeast species causing candidemia in Algeria: the urgent need for antifungal stewardship and infection control measures
ConclusionsCollectively, our data suggest an urgent need for antifungal stewardship and infection control strategies to improve the clinical outcome of Algerian patients with candidemia. The high prevalence ofC. tropicalis joined by fluconazole-resistance may hamper the therapeutic efficacy of fluconazole, the frontline antifungal drug used in Algeria.
Publication date: June 2020Source: Journal of Global Antimicrobial Resistance, Volume 21Author(s): Marilyn M. Ninan, Rani D. Sahni, Binila Chacko, V. Balaji, Joy S. Michael
With antimicrobial resistance (AMR) increasing around the world, new research led by the University of Bristol has shown a new drug formulation could possibly be used in antifungal treatments against Candida infections.
Publication date: Available online 25 April 2020Source: Journal of Global Antimicrobial ResistanceAuthor(s): Shweta Singh, Zeeshan Fatima, Saif Hameed
Publication date: Available online 24 April 2020Source: Journal of Global Antimicrobial ResistanceAuthor(s): Saikat Paul, Shreya Singh, Dipti Sharma, Arunaloke Chakrabarti, Shivaprakash M. Rudramurthy, Anup K. Ghosh
Conclusion: The leaf latex and TLC fractions were found to be active against the tested bacterial and Candida species. Therefore, this finding supports the traditional claim of Aloe adigratana and the need for characterization of the TLC fractions to provide as lead compounds for further comprehensive antibacterial and antifungal activities. PMID: 32308717 [PubMed]
In conclusion, the ePlex BCID-GP Panel compares favorably to SOC and targeted molecular methods for the identification of 20 Gram-positive pathogens and four antimicrobial resistance genes in positive blood culture bottles. This panel detects a broad range of pathogens and mixed infections with yeast and Gram-negative organisms from the same positive blood culture bottle.
In a separate study, HHS finds a 40% increase in sepsis cases, as more patients succumb to infections without effective antibiotics and antimicrobial drugs Given the drastic steps being taken to slow the spread of the Coronavirus in America, it’s easy to forget that significant numbers of patients die each year due to antibiotic-resistant bacteria […]
ConclusionOverexpression in efflux pump transporter genes together with mutations in ERG11 pave the way to fluconazole resistance among C. tropicalis. To the best of our knowledge this is the first study on C. tropicalis fluconazole resistance mechanism from North India region.
CONCLUSIONS: These results is very important to highlight hygienic status of paper currencies. This can be considered as an indication that banknotes may contribute to the spread of pathogens and antimicrobial resistance. Therefore, we may need to start using alternative products instead of banknotes. PMID: 32066229 [PubMed - as supplied by publisher]
Although rare, Candida auris resistant to all three classes of commonly used antifungal drugs was identified in three patients in New York. CDC considers C. auris an urgent threat, the highest category of concern.