Genome-wide CRISPR knockout screens identify ADAMTSL3 and PTEN genes as suppressors of HCC proliferation and metastasis, respectively

ConclusionsUsing both in vitro and in vivo approaches, we described the profound role of theADAMTSL3 andPTEN genes. This study indicates novel candidate targets for use in HCC treatment and therapy.
Source: Journal of Cancer Research and Clinical Oncology - Category: Cancer & Oncology Source Type: research