Burden of metastatic bone disease measured on 18F-NaF PET/computed tomography studies as a prognostic indicator in patients with medullary thyroid cancer

Conclusion In patients with MTC, the burden of metastatic bone disease is associated with OS.
Source: Nuclear Medicine Communications - Category: Nuclear Medicine Tags: Original Articles Source Type: research

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BACKGROUND AND PURPOSE: During thyroidectomy incomplete resection of the thyroid gland may occur. This complicates the imaging surveillance of these patients as residual thyroid needs to be distinguished from local recurrence. Therefore, the purpose of this study was to determine if multiphasic multi-detector computed tomography (4D-MDCT) can differentiate residual nonmalignant thyroid tissue and recurrent thyroid carcinoma after thyroidectomy. MATERIALS AND METHODS: In this retrospective study, Hounsfield unit values on multiphasic multidetector CT in precontrast, arterial (25 seconds), venous (55 seconds), and delayed (...
Source: American Journal of Neuroradiology - Category: Radiology Authors: Tags: HEAD & amp; NECK Source Type: research
Authors: Cho SJ, Baek SM, Lim HK, Lee KD, Son JM, Baek JH Abstract BACKGROUND: Despite reports describing favorable short-term results for thermal ablation of thyroid cancer, there remains a need to evaluate long-term results because of its indolent characteristics. The purpose of this study was to evaluate the long-term efficacy and safety of ultrasound (US)-guided radiofrequency ablation (RFA) for low-risk papillary thyroid microcarcinoma (PTMC) over a follow-up period of more than 5 years. METHODS: From a cohort of patients under surveillance following US-guided RFA for primary low-risk PTMC, those with a re...
Source: Thyroid : official journal of the American Thyroid Association - Category: Endocrinology Tags: Thyroid Source Type: research
Sun-Won Park Diagnostic accuracy of US in the evaluation of lymph node (LN) metastasis for thyroid cancer patients is limited. We investigated the value of CT added to US for characterizing LNs in preoperative thyroid cancer patients by node-by-node correlation. A total of 225 primary thyroid cancer patients who underwent LN biopsy were included. Based on node-by-node correlation, 274 LNs were classified into probably benign, indeterminate, and suspicious categories on US, CT, and combined US/CT. Malignancy risks were calculated for each category and were compared between US/CT concordant and discordant cases. On US...
Source: Cancers - Category: Cancer & Oncology Authors: Tags: Article Source Type: research
Cancer Biotherapy and Radiopharmaceuticals, Ahead of Print.
Source: Cancer Biotherapy and Radiopharmaceuticals - Category: Cancer & Oncology Authors: Source Type: research
AbstractObjectivesTo investigate the diagnostic impact and performance of spectral dual-layer detector CT in the detection and characterization of cancer compared to conventional CE-CT.MethodsIn a national workup program for occult cancer, 503 patients (286 females and 217 males) were prospectively enrolled for a contrast-enhanced spectral CT scan. The readings were performed with and without spectral data available. A minimum of 3  months between interpretations was implemented to minimize recall bias. The sequence of reads for the individual patient was randomized. Readers were blinded for patient identifiers and cl...
Source: European Radiology - Category: Radiology Source Type: research
Conclusions: MDCT scanning is accurately imaging modality for the evaluation of synchronous lymphoma and other solid malignancies. More reports and accumulation of such cases should help to clarify the mechanisms, contribute to a further understanding of this phenomenon, and may lead to a new treatment strategy for synchronous lymphoma and other solid malignancies.
Source: Journal of Cancer Research and Therapeutics - Category: Cancer & Oncology Authors: Source Type: research
Although ultrasonography (US) is a standard technique for the assessment of cervical lymph node (LN) metastasis, the role of F-18 fluorodeoxyglucose (FDG) positron emission tomography-computed tomography (PET-CT) is increasingly reported. The purpose of this study is to assess the diagnostic accuracy of F-18 FDG PET-CT for detection of cervical LN metastasis in thyroid cancer (TCa) patients through a meta-analysis.
Source: Clinical Imaging - Category: Radiology Authors: Tags: Molecular Imaging and Nuclear Medicine Source Type: research
Have incidental findings from low-dose CT scans performed for lung cancer screening contributed to an increasing incidence and overdiagnosis of thyroid cancer?American Journal of Epidemiology
Source: Medscape Today Headlines - Category: Consumer Health News Tags: Public Health & Prevention Journal Article Source Type: news
Conclusions This FASpecT/CT acquisition in radioiodine-treated DTC offers the potential of higher sensitivity for metastatic lymph node detection in low count rates and a significant decrease in imaging time in high count rates. These advantages make SPECT/CT imaging more acceptable for patients who have difficulty with longer imaging times, to include the pediatric population.
Source: Clinical Nuclear Medicine - Category: Nuclear Medicine Tags: Original Articles Source Type: research
AbstractPurposeThe purpose of this study was to compare dynamic18F-FGln PET/CT images of healthy subjects and cancer patients and explore the best imaging phase for different cancers.MethodsThirteen healthy volunteers and 31 cancer patients separately underwent18F-FGln and18F-FDG PET/CT scans within 1  week. The distributions of18F-FGln and18F-FDG in the whole body and the tumor avidity were analyzed and compared. The tumor maximum standardized uptake values (SUVmax) and tumor-to-nontumor SUV ratio (SUR) of18F-FGln/PET at different scan phases were compared.ResultsCompared to the healthy subjects, the cancer patients ...
Source: European Journal of Nuclear Medicine and Molecular Imaging - Category: Nuclear Medicine Source Type: research
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