Preeclampsia beyond pregnancy:Long-term consequences for mother and child.

Preeclampsia beyond pregnancy:Long-term consequences for mother and child. Am J Physiol Renal Physiol. 2020 Apr 06;: Authors: Turbeville HR, Sasser JM Abstract Preeclampsia is defined as new-onset hypertension after the 20th week of gestation along with evidence of maternal organ failure. Rates of preeclampsia have steadily increased over the past 30 years, affecting approximately 4% of pregnancies in the United States and causing a high economic burden. The pathogenesis is multifactorial, with acknowledged contributions by placental, vascular, renal, and immunological dysfunction. Treatment is limited, commonly employing symptomatic management and/or early delivery of the fetus. Along with significant peripartum morbidity and mortality, current research continues to demonstrate that the consequences of preeclampsia extend far beyond preterm delivery. It has lasting effects for both mother and child, resulting in increased susceptibility to hypertension and chronic kidney disease, yielding lifelong risk to both individuals. This review discusses recent guideline updates and recommendations, along with current research on these long-term consequences of preeclampsia. PMID: 32249616 [PubMed - as supplied by publisher]
Source: Am J Physiol Renal P... - Category: Urology & Nephrology Authors: Tags: Am J Physiol Renal Physiol Source Type: research