Urbanization, urbanicity, and depression: a review of the recent global literature
Purpose of review One of the defining trends of population movement in the last half century has been global urbanization. Depression is the most common mental disorder in the world, but it is unclear how urbanization and urban living affect depression outcomes. Grounded in a previously articulated conceptual framework, we systematically reviewed recently published studies on urbanization, urbanicity, and depression. Recent findings Eleven articles were included in this review. Four studies found that living in urban areas was associated with elevated odds or more symptoms of depression. Three studies – all done in China – estimated protective effects of urbanization or urbanicity on depression. Two studies concluded no overall clear association. The remaining two articles stratified by urbanicity and found that greenspace was inversely associated with depression in more densely populated areas relative to rural areas. Other themes discussed included global and national trends such as aging, immigration, and planned urbanization in China, as well as urban living conditions such as traffic noise, air pollution, proximity to roadways, neighborhood social capital, and social cohesion. Summary Urbanization may affect depression differentially across geographic regions and income levels. More research is needed, particularly in low-income and middle-income countries, and on intersections between urbanization and other emerging global trends.
Publication date: Available online 26 May 2020Source: NeuroImage: ClinicalAuthor(s): Sonsoles Alonso Martínez, Jan-Bernard C. Marsman, Morten L. Kringelbach, Gustavo Deco, Gert J. ter Horst
Publication date: Available online 30 May 2020Source: Social Science &MedicineAuthor(s): Jonathan M. Platt, Lisa Bates, Justin Jager, Katie A. McLaughlin, Katherine M. Keyes
Behavioral health (BH) complaints, including suicidal ideation (SI) and alcohol, are common in US Emergency Departments (EDs), [1-3]. The CDC published data in 2018 demonstrating a 25% overall increase in ED visits for SI and/or self-directed violence . Additionally, the CDC reported that 24.5% of the population > 12 years old engaged in binge alcohol use in 2017 . A public health crisis occurred with the onset of novel coronavirus 2019 (COVID-19). Current “stay at home” orders have reduced human contact through social distancing .
Translational Psychiatry, Published online: 01 June 2020; doi:10.1038/s41398-020-0844-4A randomized placebo-controlled PET study of ketamine´s effect on serotonin1B receptor binding in patients with SSRI-resistant depression
ConclusionsThe grades of BPD-specific symptom severity derived from the distribution of the BSL-23 scores received consistent empirical validation from established assessments for psychopathology. Future studies should expand this validation by including additional instruments e.g., to assess self-esteem, loneliness, connectedness, and quality of life.
Publication date: Available online 30 May 2020Source: European Journal of Integrative MedicineAuthor(s): Jingyi Shao, Lingming Zhou, Tianyu Shao, Minrui Ding, Zhuqing Jin
Publication date: Available online 30 May 2020Source: Progress in Neuro-Psychopharmacology and Biological PsychiatryAuthor(s): Gianluca Serafini, Giovanna Canepa, Andrea Aguglia, Andrea Amerio, Davide Bianchi, Magnani, Bernardo Dell'Osso, Maurizio Pompili, Paul B. Fitzgerald, Mario Amore
CONCLUSIONS: This unprecedented crisis may interact with certain dimensions of the suicidal process. However, it is time to innovate. Several suicide prevention tools all have their place in new modes of care and should be tested on a large scale. PMID: 32471707 [PubMed - as supplied by publisher]
Authors: Rahimian R, Fakhfouri G, Zirak MR PMID: 32470874 [PubMed - as supplied by publisher]
miR‑205 suppresses cell migration, invasion and EMT of colon cancer by targeting mouse double minute 4. Mol Med Rep. 2020 May 18;: Authors: Fan Y, Wang K Abstract Colon cancer is one of the most frequent malignant tumors, and microRNA (miR)‑205 is involved in the tumor progression. The present study aimed to explore the effects of miR‑205 on human colon cancer and its targeting mechanism. The levels of miR‑205 and mouse double minute 4 (MDM4) were determined via reverse transcription‑quantitative (RT‑q)PCR and western blot analysis. A luciferase activity assay was performed t...