Sensors, Vol. 20, Pages 2070: Graphitic Carbon Nitride as an Amplification Platform on an Electrochemical Paper-Based Device for the Detection of Norovirus-Specific DNA
Sensors, Vol. 20, Pages 2070: Graphitic Carbon Nitride as an Amplification Platform on an Electrochemical Paper-Based Device for the Detection of Norovirus-Specific DNA Sensors doi: 10.3390/s20072070 Authors: Aditya Rana Manjari Killa Neelam Yadav Annu Mishra Ashish Mathur Arun Kumar Manika Khanuja Jagriti Narang Roberto Pilloton Norovirus is one of the leading causes of gastroenteritis, acute vomiting, intense diarrhoea, acute pain in the stomach, high fever, headaches, and body pain. Conventional methods of detection gave us very promising results but had disadvantages such as low sensitivity, cost ineffectiveness, reduced specificity and selectivity, etc. Therefore, biosensors can be a viable alternative device which can overcome all setbacks associated with the conventional method. An electrochemical sensor based on oxidized graphitic carbon nitride (Ox-g-C3N4) modified electrochemical paper-based analytical device (ePAD) was fabricated for the detection of norovirus DNA. The synthesized Ox-g-C3N4 nanosheets were characterized by field emission scanning electron microscopy (FESEM), X-ray Diffraction (XRD), UV-Vis spectroscopy and X-Ray Photoelectron Spectroscopy. The capture probe DNA (PDNA) modified electrodes were characterized by cyclic voltammetry (CV) and differential pulse voltammetry (DPV). These two characterization techniques were also employed to find the optimal scan rate, response time and temperature of the fabricated sensor. The fabri...
Do you folks have any ideas for my next PIP? I did the back pain one a few years ago and it wasn't too bad. Can I do same one (from AAPMR) again? The other projects don't really pertain to my practice. Any other recommendations?
ConclusionThe proposed multiparametric MRI-based SLICs+MTh method performs noninvasive assessment of NACT response in osteosarcoma that may improve cancer treatment monitoring, planning, and overall prognosis.Key Points• The simple linear iterative clustering supervoxels and Otsu multithresholding-based technique (SLICs+MTh) successfully estimates the proportion of necrosis, viable tumor, and edema in osteosarcoma in the course of chemotherapy.• The proposed technique is noninvasive and uses multiparametric MRI to measure necrosis as an indication of anticancer treatment response.• SLICs+MTh-based necrosis w...
ConclusionsThe e-ASPECTS software generates robust values for e-ASPECTS and acute infarct volumes when using ST ≤ 4 mm with ST = 1 mm yielding the best performance for predicting baseline stroke severity and clinical outcome after 90 days.Key Points•Clinical utility of automatically derived ASPECTS from computed tomography scans was shown in patients with acute ischemic stroke and treatment with mechanical thrombectomy.•Thin slices (= 1 mm) had the highest clinical utility in comparison with thicker slices (2–10 mm) by having the strongest correlation...
Publication date: Available online 25 May 2020Source: Academic RadiologyAuthor(s): Amel Amalou, Baris Turkbey, Sheng Xu, Evrim Turkbey, Peng An, Gianpaolo Carrafiello, Anna Maria Ierardi, Robert Suh, Hayet Amalou, Bradford J. Wood
CONCLUSIONS: The average patient is middle aged (often male) with a history of subacute back pain, sometimes presenting fever and/or neurological damage on diagnosis. Acute phase reactants are frequently raised. Diabetes mellitus, endocarditis and immunosuppressed patients may have the worst chance of a good outcome, therefore these patients should be more carefully managed (always try to obtain an imaging-guided biopsy, correct antibiotic treatment, and a functional and clinical follow-up). PMID: 32446680 [PubMed - as supplied by publisher]
Publication date: Available online 25 May 2020Source: Oral Surgery, Oral Medicine, Oral Pathology and Oral RadiologyAuthor(s): Paul Ryan, Mark Sheehy
Publication date: Available online 24 May 2020Source: Oral Surgery, Oral Medicine, Oral Pathology and Oral RadiologyAuthor(s): Mariana Y Puerta, Ricardo Galhardoni, Manoel Jacobsen Teixeira, Jose Tadeu Tesseroli de Siqueira, Silvia Regina Dowgan Tesseroli de Siqueira
Publication date: Available online 24 May 2020Source: International Journal of PharmaceuticsAuthor(s): Ľubica Vetráková, Vilém Neděla, Jiří Runštuk, Eva Tihlaříková, Dominik Heger, Evgenyi Shalaev
The reason health care systems are taking out massive bank-credit lines is they just suffered through their industry ’s worst financial month ever — and their executives don’t know when the pain will end.
CONCLUSIONS: The findings indicate that the Polish adaptation of the SBQ-R by Osman et al. has good psychometric characteristics and can be considered in both research and clinical practice. PMID: 32447359 [PubMed - as supplied by publisher]