Highly Z-selective synthesis of 1,3-oxathiol-2-ylidenes and 4-methylene-oxazolidine-2-thiones via atom specific 5-exo-dig cyclization of propargyl alcohol with isothiocyanate

Org. Biomol. Chem., 2020, Accepted Manuscript DOI: 10.1039/D0OB00083C, PaperMrinal K Bera, S. Antony Savarimuthu, D.G. Leo Prakash, S. Augustine Thomas, Thirumanavelan Gandhi DBU mediated 5-exo-dig cyclization of isothiocyanate and propargyl alcohol leading to valuable heterocyclic compounds has been accomplished. Different mode of nucleophilicity (either S-selective or N-selective) of isothiocyanates was found to... The content of this RSS Feed (c) The Royal Society of Chemistry
Source: RSC - Organic and Biomolecular Chemistry - Category: Molecular Biology Authors: Source Type: research