Africa: New Antimalarial Drug Target Identified

[MMV]Compounds that hit the target may be capable of curing, preventing and blocking the transmission of malaria
Source: AllAfrica News: Health and Medicine - Category: African Health Source Type: news

Related Links:

[Premium Times] No fewer than 16,992 children below the age of five were treated of malaria under the EU/UNICEF Maternal, New-born and Child Health and Nutrition (MNCHN) project in Adamawa.
Source: AllAfrica News: Malaria - Category: Infectious Diseases Source Type: news
Conclusion: Our findings revealed that EL significantly reduced blood uric acid levels, prevented pathological changes of kidney in PO induced hyperuricemia animal model, and improved renal urate transports. We partly clarified the mechanism was related to suppressing effect of URAT1 by quassinoid in EL. This study is the first to demonstrate that EL plays a role in hyperuricemia by promoting renal uric acid excretion.
Source: Frontiers in Pharmacology - Category: Drugs & Pharmacology Source Type: research
Resumo Este artigo avalia a rela ção de custos entre a saúde pública e a implementação do saneamento básico na capital da Guiné-Bissau. Analisaram-se seis cenários, incluindo três opções para o sistema de esgotamento sanitário (sistema coletivo com rede coletora e estação elevatória de esgoto, sistema simplificado i ndividual por latrina e sistema coletivo completo com rede coletora, estação elevatória e estação de tratamento de esgoto) e duas para o sistema de abastecimento de &...
Source: Saude e Sociedade - Category: International Medicine & Public Health Source Type: research
Resumo Este artigo avalia a rela ção de custos entre a saúde pública e a implementação do saneamento básico na capital da Guiné-Bissau. Analisaram-se seis cenários, incluindo três opções para o sistema de esgotamento sanitário (sistema coletivo com rede coletora e estação elevatória de esgoto, sistema simplificado i ndividual por latrina e sistema coletivo completo com rede coletora, estação elevatória e estação de tratamento de esgoto) e duas para o sistema de abastecimento de &...
Source: Saude e Sociedade - Category: International Medicine & Public Health Source Type: research
Learn the indications for and proper administration of tafenoquine, a newly approved option for malaria chemoprophylaxis and antirelapse therapy.Morbidity &Mortality Weekly Report
Source: Medscape Today Headlines - Category: Consumer Health News Tags: Public Health & Prevention Journal Article Source Type: news
While chicken soup has often been considered as effective as penicillin to treat many illnesses, or at least bad colds, a new study looks at different kinds of soups (yes, soups) to battle a more serious infection —malaria.
Source: Forbes.com Healthcare News - Category: Pharmaceuticals Authors: Source Type: news
Conclusions/SignificanceOur data indicate that howler monkeys act as the main reservoir for the Atlantic forest human malarial parasites in RJ and other sites in Southeast Brazil and reinforce its zoonotic characteristics.
Source: PLoS Neglected Tropical Diseases - Category: Tropical Medicine Authors: Source Type: research
Authors: de Montalembert M, Tshilolo L, Allali S Abstract As more children are appropriately being diagnosed, the burden of sickle cell disease is increasing greatly in Africa and in high-resource countries such as the United States and Europe. Early management is mandatory, but newborn screening is not implemented everywhere. Point-of-care testing devices are increasingly being used in low-resource countries, showing good sensitivity and specificity. Because the diagnosis is often traumatic for the families, the announcement should be made by an experienced person. The development of care networks is urgently requ...
Source: Hematology ASH Education Program - Category: Hematology Tags: Hematology Am Soc Hematol Educ Program Source Type: research
Authors: Montenegro-Idrogo JJ, Vargas-Gonzales R, Sihuincha M Abstract The clinical signs of malaria in HIV patients may vary depending on the immunological status of the patient. Nationally, evidence regarding co-infection is scarce. This research describes four cases from a hospital in Iquitos, Peru, of patients diagnosed with HIV infection and a positive blood test for malaria. Two of these patients had Plasmodium falciparum infection, and two had Plasmodium vivax infection. One of the patients was in the AIDS stage with poor adherence to combination antiretroviral therapy (cART), and the other three were in the...
Source: Revista Peruana de Medicina de Experimental y Salud Publica - Category: International Medicine & Public Health Tags: Rev Peru Med Exp Salud Publica Source Type: research
Authors: Bartra-More CA, Ramos-Castillo J, Mendoza-Bautista RC, Galindo-Cabello NR, Gebol-Cahuaza M, Chirinos-Palomino FJ Abstract Timely diagnosis of malaria is a strategy proposed by the World Health Organization to reduce malaria morbidity and mortality. A study was conducted to assess performance in microscopic diagnosis of malaria in the network of laboratories under the National Malaria Reference Laboratory of the National Institute of Health between 2012 and 2017. In the years of study, the laboratories obtained a rating of "acceptable" in the diagnosis of Plasmodium by 38.4%, 43.7%, 60.0%, 83.3%, ...
Source: Revista Peruana de Medicina de Experimental y Salud Publica - Category: International Medicine & Public Health Tags: Rev Peru Med Exp Salud Publica Source Type: research
More News: African Health | Health | Malaria