Peripheral Immunosenescence and Central Neuroinflammation: A Dangerous Liaison. A Dietary Approach.

CONCLUSION: Ageing is characterized by a peripheral subversion of the immune system with a condition of inflamm-ageing. Neuroinflammation and neurodegenerative diseases seem to be a central manifestation of a peripheral perturbation of the immune machinery. Dietary products and nutraceuticals may lead to a down-regulation of the oxidative and pro-inflammatory profile in ageing.
PMID: 32250234 [PubMed - as supplied by publisher]

Source: Endocrine, Metabolic and Immune Disorders Drug Targets - April 5, 2020 Category: Endocrinology Authors: Magrone T, Magrone M, Russo MA, Jirillo E Tags: Endocr Metab Immune Disord Drug Targets Source Type: research