Blue Rubber Bleb Nevus Syndrome With Multiple Cavernoma-Like Lesions on MRI: A Familial Case Report and Literature Review
Blue rubber bleb nevus syndrome (BRBNS), also called Bean's syndrome, is a rare disease associated with multiple venous malformations in the skin and gastrointestinal (GI) tract. Dermatological lesions, which are the first clinically visible manifestations, appear as skin-colored compressible protuberances or as dark-blue venous nodules, rubbery in consistency. Central nervous system (CNS) manifestations are rare, variable, non-specific, and tend to occur late in the disease, mainly reported as seizures and focal neurological deficits secondary to compression. Most cases occur sporadically, however, an autosomal dominant inheritance pattern has been reported. A 74-year-old male with history of focal epilepsy secondary to possible neurocysticercosis presented at the emergency department due to sudden onset of aphasia, left central facial paralysis, and dysphagia secondary to catastrophic intracerebral hemorrhage. Cerebral MRI showed multiple cerebral cavernous malformations (CCM)-like lesions and, on the general exploration, multiple dark-blue nodules, rubbery in consistency. One week later he died due to complicated pneumonia; a brain autopsy was performed showing multiple vascular malformations. His son had a history of focal epilepsy presumed to be related to neurocysticercosis. He had the same skin lesions and brain MRI pattern. Histological analysis of the skin lesions of the two cases showed venous vascular malformations. A non-systematic review was carried out, in which...
Publication date: September 2020Source: Epilepsy &Behavior, Volume 110Author(s): Yaretson I. Carmenate, Erie G. Gutierrez, Joon Y. Kang, Gregory L. Krauss
Publication date: Available online 25 May 2020Source: Epilepsy &BehaviorAuthor(s): Eric H. Kossoff, Zahava Turner, Jamie Adams, Stacey K. Bessone, Jennifer Avallone, Tanya J.W. McDonald, Luisa Diaz-Arias, Bobbie J. Barron, Diane Vizthum, Mackenzie C. Cervenka
Publication date: Available online 25 May 2020Source: Epilepsy &BehaviorAuthor(s): Naoto Kuroda
Cordero, a 41-year-old Tony nominee, was initially hospitalized March 30 after developing pneumonia and later tested positive for the coronavirus.
Authors: Jeżowska-Jurczyk K, Kotas R, Jurczyk P, Nowakowska-Kotas M, Budrewicz S, Pokryszko-Dragan A Abstract Mental disorders occur in patients with epilepsy significantly more frequently than in the general population or in those with other chronic diseases. The specificity of epilepsy as a condition of the central nervous system with complex somatic, psychic and social consequences contributes to co-occurrence of these disorders. Moreover, common patomechanisms are suggested for epilepsy and mental disorders, associated with disturbances of bioelectrical activity and neurotransmission in certain areas of the br...
This study aims to explore the probability of developing posttraumatic epilepsy (PTE) in the following 8 years after traumatic brain injury (TBI), the risk factors associated with PTE and its cumulative prevalence. METHODS: This is a retrospe...
Condition: Corona Virus Infection Intervention: Drug: Baricitinib Sponsor: IRCCS Policlinico S. Matteo Not yet recruiting
Conditions: COVID; Pneumonia, Viral Intervention: Device: Bedside lung ultrasound Sponsor: Kanuni Sultan Suleyman Training and Research Hospital Recruiting
Conditions: COVID 19; SARS-CoV 2; Pneumonia Interventions: Drug: Mavrilimumab; Drug: Placebos Sponsors: The Cleveland Clinic; Kiniksa Pharmaceuticals, Ltd. Recruiting