Insights about the structure of farnesyl diphosphate synthase (FPPS) and the activity of bisphosphonates on the proliferation and ultrastructure of Leishmania and Giardia

The enzyme farnesyl diphosphate synthase (FPPS) is positioned in the intersection of different sterol biosynthesis pathways such as those producing isoprenoids, dolichols and ergosterol. FPPS is ubiquitous in ...

Source: Parasites and Vectors - April 5, 2020 Category: Microbiology Authors: Ana Paula R. Gadelha, Claudia Maia Brigagao, Martha Barros da Silva, Aline Beatriz Mello Rodrigues, Ana Carolina Ramos Guimar ães, Fernando Paiva, Wanderley de Souza and Cristina Henriques Tags: Research Source Type: research