Population-based study on practice variation regarding preoperative systemic chemotherapy in patients with colorectal liver metastases and impact on short-term outcomes

Publication date: Available online 5 April 2020Source: European Journal of Surgical OncologyAuthor(s): Arthur K.E. Elfrink, Niels F.M. Kok, Leonie R. van der Werf, Myrtle F. Krul, Elske Marra, Michel W.J.M. Wouters, Cornelis Verhoef, Koert F.D. Kuhlmann, Marcel den Dulk, Rutger-Jan Swijnenburg, Wouter W. te Riele, Peter B. van den Boezem, Wouter K.G. Leclercq, Daan J. Lips, Vincent B. Nieuwenhuijs, Paul D. Gobardhan, Henk H. Hartgrink, Carlijn I. Buis, Dirk J. Grünhagen, Joost M. Klaase
Source: European Journal of Surgical Oncology (EJSO) - Category: Surgery Source Type: research

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Publication date: Available online 2 June 2020Source: Hepatobiliary &Pancreatic Diseases InternationalAuthor(s): Jinwoo Kang, Sang Hyub Lee, Jin Ho Choi, Woo Hyun Paik, Dong-Won Ahn, Ji Bong Jeong, Ji Kon Ryu, Yong-Tae Kim
Source: Hepatobiliary and Pancreatic Diseases International - Category: Gastroenterology Source Type: research
This article summarizes the latest Italian Medical Oncology Association (AIOM) guidelines on the management of cancer-related and chemotherapy-related anemia with a particular attention to the use of erythropoiesis-stimulating agents and iron supplementation. PMID: 32482149 [PubMed - as supplied by publisher]
Source: Tumori - Category: Cancer & Oncology Tags: Tumori Source Type: research
Conclusions: Two-stage surgical strategy is feasible for bulky PMP patients and it is associated with little high-grade morbidity and enhanced visceral sparing. PMID: 32484014 [PubMed - in process]
Source: International Journal of Hyperthermia - Category: Internal Medicine Tags: Int J Hyperthermia Source Type: research
Authors: Gomes I, de Almeida BP, Dâmaso S, Mansinho A, Correia I, Henriques S, Cruz-Duarte R, Vilhais G, Félix P, Alves P, Corredeira P, Barbosa-Morais NL, Costa L, Casimiro S Abstract The role of RANKL-RANK pathway in progesterone-driven mammary carcinogenesis and triple negative breast cancer tumorigenesis has been well characterized. However, and despite evidences of the existence of RANK-positive hormone receptor (HR)-positive breast tumors, the implication of RANK expression in HR-positive breast cancers has not been addressed before. Here, we report that RANK pathway affects the expression of cel...
Source: Oncotarget - Category: Cancer & Oncology Tags: Oncotarget Source Type: research
Publication date: Available online 1 June 2020Source: Journal of Bone OncologyAuthor(s): Ling Zhou, Jiadai Tang, Fengdi Hu, Yedan Liao, Rong Li, Yonghong Zhou, Zhihong Yao, Zhengqin Geng, Zuozhang Yang, Xueqi Zhang, Lin Xie
Source: Journal of Bone Oncology - Category: Cancer & Oncology Source Type: research
Chemotherapy-induced nausea and vomiting (CINV) is a common and distressing side effect. We conducted this clinical trial to compare the effectiveness of true acupuncture vs. sham acupuncture in controlling ch...
Source: Chinese Medicine - Category: Complementary Medicine Authors: Tags: Research Source Type: research
Therapeutic options for patients with hepatocellular carcinoma (HCC) are limited. Transarterial chemoembolization (TACE) is an interventional procedure used to deliver chemotherapy and embolizing agents direct...
Source: Journal of Experimental and Clinical Cancer Research - Category: Cancer & Oncology Authors: Tags: Research Source Type: research
This study is an evaluation of patient characteristics, clinicopathologic features, diagnostic tools, therapeutic options, risk factors for recurrence, and distant metastasis and follow-up findings in patients with PTs. One hundred twenty-seven patients with pathologica lly proved PTs in the National Cancer Institute, Cairo University, Egypt, from January 2011 to January 2016 were reviewed and analyzed. Sixty patients presented with benign PTs (47.2%), 34 had borderline PTs (26.8%), and 33 had malignant PTs (26%). The mean follow-up period was approximately 36 mon ths; local recurrence occurred in 34 patients, 9 benig...
Source: Indian Journal of Surgical Oncology - Category: Cancer & Oncology Source Type: research
Beneficial Microbes, Ahead of Print.
Source: Beneficial Microbes - Category: Gastroenterology Authors: Source Type: research
AbstractCurrent standard-of-care treatment for advanced pancreatic ductal adenocarcinoma is mainly based on conventional cytotoxic chemotherapy. Until recently, no randomized clinical trials had shown any clinically meaningful outcome benefit from targeted therapy in this indication. This is in contrast to many other tumor types. The majority of pancreatic tumors are driven by KRAS mutations, which are generally not amenable to targeted therapy. Driving mutations in the BRAF oncogene have proven to be an interesting molecular target in the management of advanced melanoma and colorectal adenocarcinoma and can be found in 3%...
Source: Targeted Oncology - Category: Cancer & Oncology Source Type: research
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