B Cell Tetherin: A Flow Cytometric Cell ‐Specific Assay for Response to Type I Interferon Predicts Clinical Features and Flares in Systemic Lupus Erythematosus
ConclusionOur findings indicate that memory B cell surface tetherin, a B cell –specific IFN assay, is associated with SLE diagnosis and disease activity, and predicts flares better than tetherin on other cell subsets or whole blood assays, as determined in an independent validation cohort.
Source: Arthritis and Rheumatology - Category: Rheumatology Authors: Yasser M. El ‐Sherbiny,
Md Yuzaiful Md Yusof,
Antonios Psarras,
Elizabeth M. A. Hensor,
Kumba Z. Kabba,
Katherine Dutton,
Alaa A. A. Mohamed,
Dirk Elewaut,
Dennis McGonagle,
Reuben Tooze,
Gina Doody,
Miriam Wittmann,
Paul Emery,
Edward M. V Tags: Original Article Source Type: research
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