Assessment of cardiac mechanics and biomarkers during headache attack in migraine patients with aura: a prospective study

In this study, we aimed to assess LV functions with the utility of two-dimensional speckle tracking echocardiography (2D-STE) and cardiac biomarkers with respect to the headache-free and attack periods and frequency of migraine attacks. Sixty-eight patients with MA were enrolled. During headache-free and attack periods, all patients underwent echocardiographic examination including 2D-STE, and cardiac biomarkers, B-type natriuretic peptide (BNP) and high sensitive cTnT (hs-cTnT) were studied. The impact of headache periods and frequency of attacks on cardiac mechanics and biomarkers were investigated. The mean age of study population was 38.1  ± 7.7 years (56 female) and thirty-one patients (44.6%) had high-frequency migraine attacks. Patients who suffered headache-attack periods had higher frequency of detectable hs-cTnT levels and increased NT-proBNP values which did not differ between low- and high-frequency migraine groups in b oth periods. Headache attack periods had decreased global longitudinal strain (GLS), increased LV end-systolic volume (LVESV), E/Em ratio and LV torsion (LV-tor) during headache-attack periods. In multivariate analysis; LVESV, LV-tor and high frequency of migraine attacks were associated with decrea sed GLS (≤ − 20.8), (p 0.038, p 0.026 and p 0.013, respectively). Consequently, 2D-STE findings revealed that migraine attacks, especially with increasing frequencies, could have negative impact on LV mec...
Source: The International Journal of Cardiovascular Imaging - Category: Radiology Source Type: research

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Publication date: Available online 29 May 2020Source: Neurología (English Edition)Author(s): F. Castillo-Álvarez, N. González-García, M.L. Cuadrado, J. Porta-Etessam
Source: Neurologia - Category: Neurology Source Type: research
Abstract Cerebral venous thrombosis (CVT) is an uncommon cause of stroke that mainly affects young adults with known risk factors of prothrombotic conditions, pregnancy, infection, malignancy, and drugs. Dutasteride is a 5α-reductase inhibitor that is used for benign prostate hypertrophy and androgenetic alopecia. To date, CVT caused by dutasteride use has not been reported. A 25-year-old male presented with headache and diplopia. He had taken 0.5 mg of dutasteride every other day for 9 months to treat alopecia. A headache developed 7 months after he started taking medication, and horizontal diplopia occurre...
Source: Yonsei Medical Journal - Category: Universities & Medical Training Authors: Tags: Yonsei Med J Source Type: research
PMID: 32467220 [PubMed - in process]
Source: The British Journal of General Practice - Category: Primary Care Authors: Tags: Br J Gen Pract Source Type: research
BACKGROUND: Vestibular symptoms and balance changes are common in patients with migraine, especially in the ones with aura and chronic migraine. However, it is not known if the balance changes are determined by the presence of vestibular symptoms or migrai...
Source: SafetyLit - Category: International Medicine & Public Health Tags: Ergonomics, Human Factors, Anthropometrics, Physiology Source Type: news
AbstractClinical features of COVID-19 have been mostly described in hospitalized patients with and without ICU admission. Yet, up to 80% of patients are managed in an outpatient setting. This population is poorly documented. In France, health authorities recommend outpatient management of patients presenting mild-to-moderate COVID-19 symptoms. The aim of this study was to describe their clinical characteristics. The study took place in an emergency medical dispatching center located in the Greater Paris region. Patients included in this survey met confirmed COVID-19 infection criteria according to the WHO definition. We in...
Source: Internal and Emergency Medicine - Category: Emergency Medicine Source Type: research
PMID: 32472695 [PubMed - as supplied by publisher]
Source: Headache - Category: Neurology Authors: Tags: Headache Source Type: research
Am J Perinatol DOI: 10.1055/s-0040-1712170 Objective Emergent postpartum hospital encounters in the first 42 days after birth are estimated to complicate 5 to 12% of births. Approximately 2% of these visits result in admission. Data on emergent visits and admissions are critically needed to address the current maternal morbidity crisis. Our objective is to characterize trends in emergent postpartum hospital encounters and readmissions through chief complaints and admission diagnoses over a 4.5-year period. Study Design All postpartum hospital encounters within 42 days of delivery at our institution from 201...
Source: American Journal of Perinatology - Category: Perinatology & Neonatology Authors: Tags: SMFM Fellowship Series Article Source Type: research
We report the case of an 8-year-old child suspected to have postdural puncture headache after multiple lumbar punctures for collection of cerebrospinal fluid for analysis. His symptoms included headache, nonprojectile vomiting, and lethargy. When conservative management failed, an epidural blood patch was applied and the depth of the epidural space was determined using MRI. Epidural blood patch treatment was successful, and an epidural catheter was left in situ, in case a second patch was required.
Source: Saudi Journal of Anaesthesia - Category: Anesthesiology Authors: Source Type: research
AbstractWe read with interest, the article by Gidl öf et al on the management of a twin pregnancy with severe preeclampsia and Coronavirus disease‐2019 (Covid‐19) and their call for more liberal testing guidelines in women with high‐risk pregnancies, and agree with their suggestion. A severe complication of preeclampsia is eclampsia. Presenta tions include neurological manifestations such as headache, seizures, loss of consciousness, along with raised blood pressure.
Source: Acta Obstetricia et Gynecologica Scandinavica - Category: OBGYN Authors: Tags: LETTER TO EDITOR Source Type: research
Alex NowrastehThe Chinese government ’s crackdown on dissidents in Hong Kong is just another indication of that government ’s rising totalitarianism. Vox’s Matt Yglesiaswrote that the United States should let in any Hongkonger who wishes to leave – a proposal I agree with. However, the U.S. government is moving in the opposite direction. Not only has it virtually ended all immigration, including for those seeking refuge and asylum, but it will soon go further to limit the migration of Chinese students.Senators Tom Cotton (R-AR) and Marsha Blackburn (R-TN) recently introduced theSecure...
Source: Cato-at-liberty - Category: American Health Authors: Source Type: blogs
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