Safety and Efficacy of Bariatric and Metabolic Surgery

AbstractPurpose of ReviewBariatric surgery is the most effective and durable method for treating obesity. This review highlights the results and safety of bariatric surgery.Recent FindingsThe global prevalence of obesity and its related comorbidities including cancer are on the rise. Bariatric surgery has demonstrated more robust and durable weight loss than current medical treatment. Bariatric surgery also reduces significantly the risk of complications associated with obesity comorbidities, such as diabetes and cardiovascular disease, and the risk of mortality in comparison with medical management. Due to accreditation efforts, the safety profile of bariatric surgery is equivalent or superior to many common operations.SummaryObesity is associated with increased all cause morbidity and mortality. The current bariatric procedures produce significant and durable weight loss and reduce the morbidity and mortality associated with obesity-related diseases substantially. The risk/benefit ratio for bariatric surgery is decidedly in favor for the benefit for bariatric surgery.
Source: Current Obesity Reports - Category: Eating Disorders & Weight Management Source Type: research

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It is estimated that 71% of all newly diagnosed primary liver cancer cases in America are potentially preventable. Leading risk factors linked to its occurrence are alcohol abuse, obesity, and diabetes. The primary objective of our study is to determine the impact of bariatric surgery (BaSurg) on the probability of developing liver cancer and define the primary risk factors in a severely obese patient population.
Source: Journal of the American College of Surgeons - Category: Surgery Authors: Tags: Bariatric and foregut Source Type: research
The most predisposing risk factors for Colorectal cancer (CRC) in an exclusively severely-obese-population remain to be elucidated. Additionally, the evidence regarding the relationship between CRC and diabetes mellitus (DM) is inconsistent. The primary objectives of our study are to determine the impact of bariatric surgery (BaSurg) on the probability of developing CRC and to define the primary risk factors in a severely obese patient population.
Source: Journal of the American College of Surgeons - Category: Surgery Authors: Tags: Bariatric and Foregut Source Type: research
Abstract The alarming rise in obesity and relative lack of pharmacotherapies to treat, what is becoming a global epidemic, has necessitated that an increasing number of bariatric procedures be performed. Several surgical techniques have been developed during the last 50 years and the advent of laparoscopic surgery has increased the safety and efficacy of these procedures. Bariatric surgery is by a substantial margin, the most efficacious means of achieving sustained weight loss maintenance in patients with obesity. Roux-en-Y gastric bypass surgery (RYGB) elicits the most favourable metabolic outcomes with attendan...
Source: Appetite - Category: Nutrition Authors: Tags: Appetite Source Type: research
Conclusion: Despite obesity represents a risk factor involved in the carcinogenesis, the role of the bariatric surgery in the oncological setting is not well established. In this clinical case, we benefited from the weight loss produced by bariatric surgery combined with an effective hypertrophy technique and chemotherapy. These findings suggest that bariatric surgery could be useful for obese patients with liver malignancy and need for extended hepatectomy.
Source: Medicine - Category: Internal Medicine Tags: Research Article: Clinical Case Report Source Type: research
The superiority of bariatric surgery over best medical therapy (BMT) in the treatment of type 2 diabetes has been well demonstrated in high-quality randomized clinical trials. Furthermore, there is sufficient clinical and mechanistic evidence to support consideration of metabolic surgery for the patients with class 1 obesity (body mass index [BMI], 30.0-34.9; calculated as weight in kilograms divided by height in meters squared), type 2 diabetes, and inadequately controlled hyperglycemia. At 5-year follow-up, compared with BMT, the Systemic Therapy in Advancing or Metastatic Prostate Cancer: Evaluation of Drug Efficacy (ST...
Source: JAMA Surgery - Category: Sports Medicine Source Type: research
CONCLUSION: Apart from eliminating metabolic disorders, SG improves endothelial function and plays a protective role in preventing lung cancer via normalized ET-1 axis and reduced DNA damage. PMID: 32523314 [PubMed - in process]
Source: World Journal of Gastroenterology : WJG - Category: Gastroenterology Authors: Tags: World J Gastroenterol Source Type: research
Farrell Endometrial cancer is one of the most common cancers in women worldwide and its incidence is increasing. Epidemiological evidence shows a strong association between endometrial cancer and obesity, and multiple mechanisms linking obesity and cancer progression have been described. However, it remains unclear which factors are the main drivers of endometrial cancer development. Hyperglycemia and type 2 diabetes mellitus are common co-morbidities of obesity, and there is evidence that hyperglycemia is a risk factor for endometrial cancer independent of obesity. This review aims to explore the association betwee...
Source: Cancers - Category: Cancer & Oncology Authors: Tags: Review Source Type: research
Obesity is a serious, chronic, treatable, and global disease epidemic. Over 98 million people currently have the disease of obesity, and in a recent New England Journal of Medicine article, Harvard researchers predicted that by 2030, 50% of the population in the United States will have the disease of obesity. Type 2 diabetes (T2D) is significantly associated with obesity. While many people with obesity do not have diabetes, most people with T2D have the disease of obesity. Excess adiposity (body fat storage), which is present in obesity, contributes to many chronic diseases beyond T2D. These include high blood pressure, he...
Source: Harvard Health Blog - Category: Consumer Health News Authors: Tags: Diabetes Diet and Weight Loss Health Heart Health Surgery Source Type: blogs
ConclusionCompared with controls, bariatric surgery reduces long-term global mortality only above median age, not below median age. Also mortality due to specific causes is mainly reduced in persons above median age.
Source: Obesity Surgery - Category: Surgery Source Type: research
Right now, one in 12 children and adolescents in the US are severely obese. If that isn’t startling enough, consider this: among 12-to-15-year-olds, that number jumps to one in 10 — and among 16-to-19-year-olds, it is one in seven. According to the American Academy of Pediatrics (AAP), the best hope for many of these youths may be bariatric surgery. Bariatric surgery is surgery that helps with weight loss by making the stomach smaller and making other changes in the digestive system. It’s jarring to think about doing irreversible surgery on an adolescent — or a child, as the AAP discourages age limi...
Source: Harvard Health Blog - Category: Consumer Health News Authors: Tags: Adolescent health Children's Health Diabetes Diet and Weight Loss Parenting Source Type: blogs
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