Treatment of frail older adults and elderly patients with philadelphia chromosome-negative acute lymphoblastic leukemia: results of a prospective trial with minimal chemotherapy

In a series of 72 older and elderly frail patients (Charlson Comorbidity Index ≥4) with Philadelphia chromosome-negative ALL prospectively treated with very attenuated chemotherapy regimen (vincristine, dexamethasone, methotrexate and mercaptopurine) the rate of complete remission was 54%, with overall survival probability of 7.6 months. Patients with ECOG score

Source: Clinical Lymphoma, Myeloma and Leukemia - April 4, 2020 Category: Hematology Authors: Josep-Maria Ribera, Olga Garc ía, Eduardo Cerello Chapchap, Cristina Gil, José González-Campos, Pere Barba, María-Luz Amigo, María-José Moreno, Esperanza Lavilla, Natalia Alonso, Juan-Miguel Bergua, Mar Tormo, Jordi Ribera, Magdalena Sierra, Daniel Tags: Original Study Source Type: research