Migraine and Ischemic Stroke in Women. A Narrative Review.
Migraine and Ischemic Stroke in Women. A Narrative Review. Headache. 2020 Apr 04;: Authors: Tietjen GE, Maly EF Abstract OBJECTIVE/BACKGROUND: Migraine is associated with ischemic stroke. Women are 3-fold as likely as men to have migraine, and high estrogen states increase the risk of migraine with aura (MWA), venous thromboembolism (VTE), and of stroke. We review the epidemiological and mechanistic evidence of the migraine-stroke relationship and its risk factors, with a focus on women and conditions that exclusively or predominantly affect them. METHODS: We performed a search of MEDLINE/PubMed database, then a narrative review of the epidemiological evidence of the migraine-stroke relationship as well as the evidence for arterial, thrombophilic, and cardiac mechanisms to explain this connection. We examine the implications of this evidence for the diagnostic evaluation and treatment of MWA. RESULTS: MWA is associated with multiple stroke risk factors, such as hypertension, hyperlipidemia, diabetes mellitus, cigarette smoking, atrial fibrillation, and patent foramen ovale. In women, MWA is also associated with biomarkers of endothelial activation, hormonal contraceptive use, pregnancy, and VTE. This suggests that a subset of auras may be secondary, that is, induced by ischemia related to microemboli or in situ thrombosis. MWA-associated ischemic stroke is more common in young (
Publication date: Available online 30 May 2020Source: Journal of American Association for Pediatric Ophthalmology and StrabismusAuthor(s): Gamze Dereli Can, Muhammet Furkan Korkmaz, Mehmet Erol Can
Publication date: Available online 30 May 2020Source: Journal of the Formosan Medical AssociationAuthor(s): Jia-Kang Wang, Tzu-Lun Huang, Pei-Yao Chang
[Frequency and predictive factors of venous thrombosis in Behçet's disease]. Rev Med Interne. 2020 May 26;: Authors: Ha-Ou-Nou FZ, Essaadouni L Abstract OBJECTIVE: To investigate the clinical features of venous thrombosis in patients with Behçet's disease and to determine the patients at high risk for this complication. METHODS: We retrospectively studied patients with venous thrombosis (n = 157) who were followed up in the Internal Medicine department. These patients were divided into two groups according to the existence (n = 60, 38.2%) or not (n = 97, 61.8%) of Beh&cced...
Publication date: Available online 30 May 2020Source: Diabetes &Metabolic Syndrome: Clinical Research &ReviewsAuthor(s): Hema S. Gopalan, Anoop Misra
Publication date: Available online 30 May 2020Source: Diabetes &Metabolic Syndrome: Clinical Research &ReviewsAuthor(s): Sachin Atre, Sona Deshmukh, Manjusha Kulkarni
Publication date: 15 September 2020Source: Journal of Ethnopharmacology, Volume 259Author(s): Junnan Ma, Xianglong Meng, Yi Liu, Cheng Yin, Tong Zhang, Piao Wang, Yong-Ki Park, Hyo Won Jung
Authors: Li Y, Du L, Tang X, Chen Y, Mei D Abstract BACKGROUND: Rivaroxaban, a novel oral anticoagulant drug, is widely used in clinical practice. There is no standardized laboratory monitoring for rivaroxaban, and its plasma concentration in Chinese patients with deep vein thrombosis is unclear. The rivaroxaban concentrations in human plasma and determine the steady-state concentration of rivaroxaban in patients with deep vein thrombosis are needed. METHODS: An ultra-high-performance liquid chromatography with mass spectrometric detection method was developed. Chromatographic separation was performed on a Wate...
Osborne H Abstract The calcium-sensing receptor (CaSR) is a class C G protein-coupled receptor that responds to multiple endogenous agonists and allosteric modulators, including divalent and trivalent cations, L-amino acids, γ-glutamyl peptides, polyamines, polycationic peptides, and protons. The CaSR plays a critical role in extracellular calcium (Ca2+ o) homeostasis, as demonstrated by the many naturally occurring mutations in the CaSR or its signaling partners that cause Ca2+ o homeostasis disorders. However, CaSR tissue expression in mammals is broad and includes tissues unrelated to Ca2+ o homeostasis, ...
Publication date: Available online 30 May 2020Source: EXPLOREAuthor(s): Lena Sagi-Dain, Shlomi Sagi
Publication date: Available online 30 May 2020Source: European Journal of Integrative MedicineAuthor(s): Jingyi Shao, Lingming Zhou, Tianyu Shao, Minrui Ding, Zhuqing Jin