Reduction in Filamin C transcript is associated with arrhythmogenic cardiomyopathy in Ashkenazi Jews

Filamin C is a cytoskeletal protein expressed in cardiac cells. Nonsense variations in the filamin C gene (FLNC) were associated with dilated and arrhythmogenic cardiomyopathies.

Source: International Journal of Cardiology - April 4, 2020 Category: Cardiology Authors: Oz Shimrit, Yonath Hagith, Visochyk Leonid, Ofek Efrat, Landa Natalie, Reznik-Wolf Haike, F. Ortiz-Genga Martin, Monserrat Lorenzo, Ben-Gal Tuvia, Goitein Orly, Beinart Roy, Glikson Michael, Freimark Dov, Pras Elon, Arad Michael, Nof Eyal Source Type: research