Initial experience with scalp sparing radiation with concurrent temozolomide and tumor treatment fields (SPARE) for patients with newly diagnosed glioblastoma.

Source: Clinical Trials And Noteworthy Treatments For Brain Tumors - Category: Cancer & Oncology Source Type: clinical trials

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CONCLUSIONS: The experiment results indicate that the proposed model yields a promising performance in automated brain tumor segmentation. PMID: 32444591 [PubMed - as supplied by publisher]
Source: Journal of X-Ray Science and Technology - Category: Radiology Tags: J Xray Sci Technol Source Type: research
Condition:   Central Nervous System Diseases Interventions:   Drug: Dexmedetomidine;   Drug: Normal saline Sponsor:   Capital Medical University Not yet recruiting
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
AbstractHere, we report on a 28-year old male patient presenting with neck and shoulder pain, dysesthesia of all four limbs and hypesthesia of both hands, without motor deficits. Magnetic resonance imaging showed an intradural, intramedullary mass of the cervical spinal cord of 6.4  cm length and 1.7 cm diameter. The patient underwent surgical resection. Histological and immunohistochemical evaluation showed pleomorphic glial tumor cells, mitoses, calcifications, and atypical ganglioid cells compatible with the morphology of anaplastic ganglioglioma (WHO Grade III). Extensiv e molecular workup revealedH3F3A K27M,...
Source: Brain Tumor Pathology - Category: Neurology Source Type: research
ConclusionsHigh uptake of68Ga-PSMA and18F-DCFPyL in the peritumoral area of all glioma models is presumably caused by activated astrocytes. This may represent a limitation for the clinical application of PSMA ligands in gliomas.
Source: EJNMMI Research - Category: Radiology Source Type: research
ConclusionsFuture studies will hopefully soon bridge the gap in our knowledge on how epigenetic modifications are linked to treatment related sequelae in pediatric brain tumor patients.
Source: Journal of Neuro-Oncology - Category: Cancer & Oncology Source Type: research
Condition:   Central Nervous System Diseases Interventions:   Drug: Dexmedetomidine;   Drug: Normal saline Sponsor:   Capital Medical University Not yet recruiting
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
We report a rare case of primary spinal intramedullary Ewing-like sarcoma harboringCIC-DUX4 translocation. A 23-year-old man presented with weakness in the extremities. Magnetic resonance imaging revealed a large intramedullary tumor spanning C3 –C5 with heterogeneous enhancement following gadolinium administration. Histologically, most of the tumor displayed dense myeloid proliferation composed of medium- to slightly small-sized primitive cells. Postoperatively, he received local adjuvant radiation therapy without tumor progression for 1 0 months. Target RNA sequencing analysis revealed theCIC-DUX4 fusion gene....
Source: Brain Tumor Pathology - Category: Neurology Source Type: research
Condition:   Central Nervous System Diseases Interventions:   Drug: Dexmedetomidine;   Drug: Normal saline Sponsor:   Capital Medical University Not yet recruiting
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
Publication date: July 2020Source: Biomedical Signal Processing and Control, Volume 60Author(s): Saroj Kumar Chandra, Manish Kumar Bajpai
Source: Biomedical Signal Processing and Control - Category: Biomedical Science Source Type: research
uya Abe Meningiomas are the most common type of intracranial brain tumors in adults. The majority of meningiomas are benign with a low risk of recurrence after resection. However, meningiomas defined as grades II or III, according to the 2016 World Health Organization (WHO) classification, termed high-grade meningiomas, frequently recur, even after gross total resection with or without adjuvant radiotherapy. Boron neutron capture therapy (BNCT) and photodynamic therapy (PDT) are novel treatment modalities for malignant brain tumors, represented by glioblastomas. Although BNCT is based on a nuclear reaction and PDT uses...
Source: Cancers - Category: Cancer & Oncology Authors: Tags: Review Source Type: research
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