Safety and feasibility of PARP1/2 imaging with 18F-PARPi in patients with head and neck cancer.

CONCLUSIONS: Imaging of head and neck cancer with 18F-PARPi is feasible and safe. 18F-PARPi detects primary and metastatic lesions, and retention in tumors is longer than in healthy tissues.
PMID: 32245901 [PubMed - as supplied by publisher]

Source: Clinical Cancer Research - April 2, 2020 Category: Cancer & Oncology Authors: Schöder HM, Demétrio De Souza França P, Nakajima R, Burnazi EM, Roberts S, Brand C, Grkovski M, Mauguen A, Dunphy MP, Ghossein R, Lyashchenko SK, Lewis JS, O'Donoghue JA, Ganly I, Patel SG, Lee NY, Reiner T Tags: Clin Cancer Res Source Type: research