Post-traumatic Curvularia sp. arthritis in an immunocompetent adult

Publication date: Available online 4 April 2020Source: Journal de Mycologie MédicaleAuthor(s): Elie Djenontin, David Lebeaux, Hans Acikgoz, Blandine Rammaert, Marie-Elisabeth Bougnoux, Claire Rouzaud, Benjamin Bouyer, Benoit Champigneulle, Eric Dannaoui
Source: Journal of Medical Mycology - Category: Biology Source Type: research

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Condition:   Trauma Injury Interventions:   Other: Immunofluorescence Imaging;   Other: DCE-MRI Sponsors:   Dartmouth-Hitchcock Medical Center;   Dartmouth College;   National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS) Not yet recruiting
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
In conclusion, our results suggest a previously unknown mechanism whereby the canonical NF-κB cascade and a mitochondrial fission pathway interdependently regulate endothelial inflammation. Lin28 as a Target for Nerve Regeneration https://www.fightaging.org/archives/2020/05/lin28-as-a-target-for-nerve-regeneration/ Researchers here show that the gene Lin28 regulates axon regrowth. In mice, raised levels of Lin28 produce greater regeneration of nerve injuries. Past research has investigated Lin28 from the standpoint of producing a more general improvement in regenerative capacity. It improves mitoch...
Source: Fight Aging! - Category: Research Authors: Tags: Newsletters Source Type: blogs
Follistatin is an inhibitor of myostatin. Blocking myostatin activity enhances muscle growth, with accompanying beneficial side-effects such as a loss of excess fat tissue. This is well proven. There are a good number of animal lineages (mice, dogs, cows, and so forth) resulting from natural or engineered myostatin loss of function mutations, and even a few well-muscled human individuals with similar mutations. A number of groups are at various stages in the development of therapies to either upregulate follistatin or inhibit myostatin. The latter is further along in the formal regulatory process: human trials have been co...
Source: Fight Aging! - Category: Research Authors: Tags: Medicine, Biotech, Research Source Type: blogs
We described changes in the glucocorticoid system and inflammatory reaction as parts of an integral system, where glucocorticoids and the glucocorticoid receptor reside at the apex of a regulatory network that blocks several inflammatory pathways, while decreased glucocorticoid signaling and/or level leads to unchecked inflammatory reactions to promote pathologies such as PTSD.Lay summary: This review emphasizes the importance of inflammatory reaction in the development of puzzling conditions sometimes observed in severe diseases including post-traumatic stress disorder -the decreased levels of glucocorticoids in the blood...
Source: Stress - Category: Research Tags: Stress Source Type: research
Olecranon fractures are intra-articular fractures that account for about 10% of all upper limb fractures [1, 2]. These fractures require anatomical reduction to prevent the development of post-traumatic arthritis and to restore the function of the triceps muscle for elbow extension [3]. Tension band wiring (TBW) has been widely used as a method of reliable fixation for these fractures, particularly for simple transverse displaced fractures of the olecranon. Although the evidence for clinical and biomechanical stability obtained using the standard TBW technique is excellent, there remains a risk of loss of the fixation, pul...
Source: Injury - Category: Orthopaedics Authors: Source Type: research
Meniscal injury is a common prelude to post-traumatic osteoarthritis (PTOA). Joint nerves can become damaged in arthritic joints leading to the manifestation of neuropathic pain. Both PTOA and neuropathic pain are more common in females; however, it is unknown whether the neural processing of joint pain is sex-specific.
Source: Osteoarthritis and Cartilage - Category: Rheumatology Authors: Source Type: research
A new review looks at the incidence of post-traumatic osteoarthritis among patients with a history of ACL injury.Arthritis Research &Therapy
Source: Medscape Today Headlines - Category: Consumer Health News Tags: Orthopaedics Journal Article Source Type: news
OBJECTIVE: To present recent evidence on the prevalence, incidence, costs, activity limitations, and work limitations of common conditions requiring rehabilitation. METHODS: This was a systematic review. Medline (PubMed), SCOPUS, Web of Science, an...
Source: SafetyLit - Category: International Medicine & Public Health Tags: Economics of Injury and Safety, PTSD, Injury Outcomes Source Type: news
This study protocol was registered in Research Registry (researchregistry5455).
Source: Medicine - Category: Internal Medicine Tags: Research Article: Study Protocol Clinical Trial Source Type: research
Introduction &Objectives Autoimmune disease is an emerging condition among persons exposed to the Sept. 11, 2001, attack on the World Trade Center (WTC) in New York. The collapse of the WTC towers after the attack resulted in the release of a cloud of dust and debris that covered parts of Lower Manhattan. Further exposure... [Read More]
Source: The Rheumatologist - Category: Rheumatology Authors: Tags: Conditions Arthritis & Rheumatology Autoimmune disease Post-Traumatic Stress Disorder (PTSD) Source Type: research
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