Clinical analgesic efficacy of pectoral nerve block in patients undergoing breast cancer surgery: A systematic review and meta-analysis

Background: Breast cancer is the most commonly diagnosed cancer in women, and more than half of breast surgery patients experience severe acute postoperative pain. This meta-analysis is designed to examine the clinical analgesic efficacy of Pecs block in patients undergoing breast cancer surgery. Methods: An electronic literature search of the Library of PubMed, EMBASE, Cochrane Library, and Web of Science databases was conducted to collect randomized controlled trials (RCTs) from inception to November 2018. These RCTs compared the effect of Pecs block in combination with general anesthesia (GA) to GA alone in mastectomy surgery. Pain scores, intraoperative and postoperative opioid consumption, time to first request for analgesia, and incidence of postoperative nausea and vomiting were analyzed. Results: Thirteen RCTs with 940 patients were included in our analysis. The use of Pecs block significantly reduced pain scores in the postanesthesia care unit (weighted mean difference [WMD] = −1.90; 95% confidence interval [CI], −2.90 to −0.91; P 
Source: Medicine - Category: Internal Medicine Tags: Research Article: Systematic Review and Meta-Analysis Source Type: research

Related Links:

ConclusionsPecs2 blocks can significantly reduce post-operative pain, nausea and vomiting in patients undergoing mastectomy. Their use can enable units to achieve high day-case mastectomy rates.
Source: Annals of Medicine and Surgery - Category: General Medicine Source Type: research
CONCLUSIONS: After mostly minor surgery for breast cancer, PECS II block was not superior to local infiltration by the surgeon. PMID: 31490251 [PubMed - as supplied by publisher]
Source: Anesthesia and Analgesia - Category: Anesthesiology Authors: Tags: Anesth Analg Source Type: research
Conclusions Pecs I is not better than a saline placebo in the presence of multimodal analgesia for breast cancer surgery. However, its role in extended (major) breast surgery may warrant further investigation. Clinical Trial Registration This study was registered at, identifier NCT01670448.
Source: Regional Anesthesia and Pain Medicine - Category: Anesthesiology Tags: Regional Anesthesia and Acute Pain: Original Articles Source Type: research
An erector spinae plane (ESP) block, firstly reported in 2016, has been shown to be able to block the dorsal and ventral rami of the thoracic spinal nerves [1,2]. Additionally, it may also block sympathetic nerve fibers [3]. Therefore, it may provide pain relief for thoracic surgery. We herein report successful use of the ESP block for combined thoracic and breast surgery. Our patient was an 83-year-old woman (148cm, 53kg) who underwent a combined left lower lobectomy for primary lung cancer and radical mastectomy for breast cancer.
Source: Journal of Clinical Anesthesia - Category: Anesthesiology Authors: Tags: Correspondence Source Type: research
CONCLUSION: Benefits of hypnosis sedation on breast cancer treatment are very encouraging and further promote the concept of integrative oncology. PMID: 29136523 [PubMed - as supplied by publisher]
Source: Breast - Category: Cancer & Oncology Authors: Tags: Breast Source Type: research
CONCLUSIONS: The Pecs block reduces postsurgical opioid consumption during the PACU stay time for patients undergoing breast surgery. PMID: 28625445 [PubMed - in process]
Source: Clinical Genitourinary Cancer - Category: Cancer & Oncology Authors: Tags: J Clin Anesth Source Type: research
Authors: Calì Cassi L, Biffoli F, Francesconi D, Petrella G, Buonomo O Abstract Breast surgery is frequently associated with postoperative pain, nausea and vomiting, that result in increased patient's suffering, prolongation of hospital stays and related costs. Thoracic paravertebral nerve block (TPVB) is a viable option to the classic multimodal analgesia in breast surgery as it enhances surgical anesthesia and postoperative analgesia. In this review, we report the results of a number of studies on the role of TPVB in breast surgery. This technique is associated with a superior control of the pain, a reduct...
Source: European Review for Medical and Pharmacological Sciences - Category: Drugs & Pharmacology Tags: Eur Rev Med Pharmacol Sci Source Type: research
It was a story with a bit of irony, as well as ominous health warnings. Crystal Hefner, the 30-year-old wife of Playboy magazine mogul Hugh Hefner, announced in a story in People magazine last month that she'd had her breast implants removed because they were making her sick. Hefner posted a photo of her post-surgery self on Instagram with the caption, "Using 2016 to reclaim my health and embrace and love myself for the real me." The former model, now a DJ, was diagnosed a few months back with Lyme disease. Her symptoms included intolerance to foods and beverages as well as back, neck, and shoulder pain. Hefn...
Source: Healthy Living - The Huffington Post - Category: Consumer Health News Source Type: news
ConclusionsBreast cancer surgery was accompanied by enormous emotional and physical distress and significant risks from bleeding and infection. Although efforts were being made to give women a greater voice and autonomy in society, their position when receiving health care remained largely a submissive one. Lack of information, feelings of vulnerability, helplessness and loss of control occurred. The public perception of detachment most likely accounted for the occasional negative stigma then associated with the surgical profession.
Source: ANZ Journal of Surgery - Category: Surgery Authors: Tags: Original Article Source Type: research
Conclusion: Benefits of hypnosis sedation on breast cancer treatment are very encouraging and further promote the concept of integrative oncology. Citation Format: Martine Berliere, Sarah Lamerant, Philippe Piette, Aurore Lafosse, Laurence Delle Vigne, Fabienne Roelants, Christine Watremez, Marie-Agnes Docquier, Lafita Fellah, Isabelle Leconte, François Duhoux. Potential benefits of hypnosis sedation on different modalities of breast cancer treatment [abstract]. In: Proceedings of the Thirty-Seventh Annual CTRC-AACR San Antonio Breast Cancer Symposium: 2014 Dec 9-13; San Antonio, TX. Philadelphia (PA): AACR; Cancer ...
Source: Cancer Research - Category: Cancer & Oncology Authors: Tags: Poster Session Abstracts Source Type: research
More News: Anesthesia | Anesthesiology | Breast Cancer | Breast Surgery | Cancer | Cancer & Oncology | Databases & Libraries | Internal Medicine | Mastectomy | Pain | Science | Women