Pitch and Duration Mismatch Negativity and Heschl's Gyrus Volume in First-Episode Schizophrenia-Spectrum Individuals.

Conclusions. pMMN and dMMN index gray matter reduction in left hemisphere auditory cortex early in psychosis, with dMMN also marginally indexing right HG volumes. This suggest conjoint functional and structural pathology that affects the automatic detection of novelty with varying degrees of penetrance prior to psychosis. These brainwaves are sensitive biomarkers of pathology early in the psychotic disease course, and may serve as biomarkers of disease progression and as therapeutic outcome measures. PMID: 32241184 [PubMed - as supplied by publisher]

https://www.ncbi.nlm.nih.gov/pubmed/32241184?dopt=Abstract

Source: Clinical EEG and Neuroscience - April 2, 2020 Category: Neuroscience Authors: Salisbury DF, Shafer AR, Murphy TK, Haigh SM, Coffman BA Tags: Clin EEG Neurosci Source Type: research