Low dose peanut challenges can facilitate infant peanut introduction regardless of skin prick test size

The Learning Early About Peanut Allergy (LEAP) trial and other studies suggest early peanut (PN) introduction prevents PN allergy in at-risk infants.1,2 In addition, PN-oral immunotherapy (PN-OIT) shows increased rates of sustained unresponsiveness in children4 mm.1 Guidelines recommend PN introduction or oral food challenge (OFC) in infants who have skin prick tests ≤7 mm and do not specifically address management of infants with SPTs>7 mm (or high PN-IgE levels).

Source: Annals of Allergy, Asthma and Immunology - April 3, 2020 Category: Allergy & Immunology Authors: Adora Lin, Burcin Uygungil, Karen Robbins, Olivia Ackerman, Hemant Sharma Tags: Letters Source Type: research