Fennel as a cause of immediate hypersensitivity to toothpaste

Ingredients in toothpaste may cause allergic and irritant contact stomatitis (Table I). Flavourings are most commonly incriminated, as they are present in 95% of toothpastes.1 Less frequently, cinnamon, fluoride and Anethole (Anise camphor) have been suggested to cause local irritation.2,3 Pruritis and flexural dermatitis to toothpaste has been reported in a 50-year-old woman sensitized to stannous fluoride (SnF2) on patch testing.4
Source: Annals of Allergy, Asthma and Immunology - Category: Allergy & Immunology Authors: Tags: Letters Source Type: research