GAD-alum immunotherapy in type 1 diabetes expands bifunctional Th1/Th2 autoreactive CD4 T cells

Conclusions/interpretationGAD-alum immunisation activates and propagates GAD-specific CD4 T cells with a distinctive bifunctional phenotype, the functional analysis of which might be important in understanding therapeutic responses.

http://link.springer.com/10.1007/s00125-020-05130-7

Source: Diabetologia - April 3, 2020 Category: Endocrinology Source Type: research