Adult-onset still & #39;s disease, an unusual cause of severe acute liver injury: A case report

SC Adiyaman, G Bengi, M Civak, M Birlik, Z Kuruuzum, C Altay, M SoyturkNigerian Journal of Clinical Practice 2020 23(4):581-585 Adult-onset Still's disease is a systemic inflammatory disease that often presents with spiking fever, typical rash, arthritis, and serositis. However, adult-onset-Still's-disease associated liver injury and acute liver failure are rare. Herein, we report a case of acute liver injury in a 23-year-old female patient with adult-onset Still's disease. She presented to the emergency department with a high fever and sore throat. She was then admitted to the department of infectious diseases with a preliminary diagnosis of an atypical respiratory infection. After being treated with antibiotics and antiviral agents, she was discharged. A few days later, she returned to the emergency department with jaundice and was rehospitalized. This time, she was admitted to the department of gastroenterology, where she was diagnosed with adult-onset Still's disease-associated acute liver injury. Eventually, the patient responded to immunosuppressive treatment with significant clinical improvement.
Source: Nigerian Journal of Clinical Practice - Category: Rural Health Authors: Source Type: research