The effect of transfusion on immune responses in thalassemia.

DISCUSSION: Tregs levels are higher in TDT patients compared to NTDT, a difference which could be ascribed to transfusion. Tregs levels and the cytokines analyzed may play little role in alloimmunization and are not impacted by the extend of iron overload. PMID: 32244102 [PubMed - as supplied by publisher]

https://www.ncbi.nlm.nih.gov/pubmed/32244102?dopt=Abstract

Source: Blood Cells, Molecules and Diseases - March 30, 2020 Category: Hematology Authors: Politou M, Komninaka V, Valsami S, Kapsimali V, Pouliakis A, Koutsouri T, Panayiotakopoulos G, Kotsianidis I, Voskaridou E Tags: Blood Cells Mol Dis Source Type: research