Can Vitamin D Reduce Heart Muscle Damage After Bypass Surgery?

Conditions:   Vitamin D Deficiency;   Cardiomyopathies;   Apoptosis;   Inflammation Interventions:   Drug: Vitamin D;   Drug: Placebo Sponsor:   Shahid Beheshti University of Medical Sciences Completed
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials

Related Links:

Condition:   Coronavirus Disease 2019 (COVID-19) Intervention:   Sponsor:   Hospital San Carlos, Madrid Recruiting
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
Vitamin D is a fat-soluble secosteroid that exerts its effects by binding to the vitamin D receptor (VDR), through which it directly and indirectly modulates the expression of hundreds to thousands of genes. While originally known for its role in regulating calcium homeostasis and metabolism, vitamin D is now associated with many other health conditions, including Parkinson's disease (PD). A high prevalence of vitamin D deficiency has been noted in PD for at least the past two decades. These findings, along with the discovery that the VDR and 1α-hydroxylase, the enzyme that converts vitamin D to its active form, are ...
Source: Frontiers in Neurology - Category: Neurology Source Type: research
This study aimed at testing the effect of vitamin D supplements on urinary megalin levels in diabetic nephropathy (DN) patients with vitamin D hypovitaminosis. METHODS: A sample of 63 participants with vitamin D deficiency with diabetic nephropathy (DN) were enrolled in the pre-post study; urinary megalin levels with various clinical parameters and serum levels of vitamin D3 were measured and compared to the baseline at 3- and 6-month intervals. RESULTS: Interestingly, a supplementation related increase in serum vitamin D3 levels at 3- and 6- month interventions affected a constellation of ameliorations in the DN p...
Source: Endocrine, Metabolic and Immune Disorders Drug Targets - Category: Drugs & Pharmacology Tags: Endocr Metab Immune Disord Drug Targets Source Type: research
Progressive Familial Intrahepatic Cholestasis Type 2 (PFIC2) is a rare congenital cholestatic liver disease that progresses to end stage liver disease. It is associated with fat soluble vitamin D deficiency ri...
Source: International Journal of Pediatric Endocrinology - Category: Endocrinology Authors: Tags: Case report Source Type: research
Conclusion: Vitamin D supplementation leads to earlier and significant improvement in TBUT, Schirmer's, and OSDI score in patients with vitamin D deficient DED.
Source: Indian Journal of Ophthalmology - Category: Opthalmology Authors: Source Type: research
Uma Sridhar, Koushik TripathyIndian Journal of Ophthalmology 2020 68(6):1026-1027
Source: Indian Journal of Ophthalmology - Category: Opthalmology Authors: Source Type: research
No abstract available
Source: Journal of Pediatric Gastroenterology and Nutrition - Category: Gastroenterology Tags: Letters to the Editor Source Type: research
Authors: Amouzegar A, Azizi F, Ashrafivand S, Ahi Z, Saleh M, Mohaghegh S, Gargari SS Abstract BACKGROUND: Calcium and vitamin D deficiency is common among Iranian women of childbearing age and poses adverse effects on pregnancy outcomes. The aim of the current study was to determine the prevalence of vitamin D and calcium in a sample of Iranian pregnant women and to assess its correlation with the feto-maternal outcomes. With this aim. METHODS: In this prospective cross-sectional study, a sample of pregnant women between 15 to 45 years who were in the third trimester were recruited from a number of hospitals i...
Source: Human Antibodies - Category: Biochemistry Tags: Hum Antibodies Source Type: research
Vitamin D deficiency is common in Crohn ’s disease (CD). High-dose vitamin D had anti-inflammatory effects in preclinical studies and trials of patients with CD. We performed a randomized trial to determine whether high-dose vitamin D prevents postoperative recurrence of CD after ileocolonic resection.
Source: Clinical Gastroenterology and Hepatology - Category: Gastroenterology Authors: Source Type: research
No abstract available
Source: Lippincott's Bone and Joint Newsletter - Category: Orthopaedics Tags: Snapshot Source Type: news
More News: Cardiology | Heart | Research | Vitamin D | Vitamin D Deficiency | Vitamins