Parametric Response Mapping of Co-registered Positron Emission Tomography and Dynamic Contrast Enhanced Computed Tomography to Identify Radio-resistant Sub-volumes in Locally Advanced Cervical Cancer

To identify sub-volumes that may predict treatment response to definitive concurrent chemoradiation therapy (CCRT) using parametric-response-mapping (PRM) of co-registered positron-emission-tomography (PET) and dynamic-contrast-enhanced (DCE) computed-tomography (CT) in locally advanced cervical carcinoma.
Source: International Journal of Radiation Oncology * Biology * Physics - Category: Radiology Authors: Source Type: research

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To identify subvolumes that may predict treatment response to definitive concurrent chemoradiation therapy using parametric response mapping (PRM) of coregistered positron emission tomography (PET) and dynamic contrast-enhanced (DCE) computed tomography (CT) in locally advanced cervical carcinoma.
Source: International Journal of Radiation Oncology * Biology * Physics - Category: Radiology Authors: Tags: Physics Contribution Source Type: research
ConclusionThe pre-therapeutic clinical evaluation of lymphatic outgrowth is over-staged. OS decreases with increasing LNR divided by the number of dissected lymph nodes. Renal insufficiency and anemia are significant negative factors, decreasing both OS and DFS.
Source: European Archives of Oto-Rhino-Laryngology - Category: ENT & OMF Source Type: research
CONCLUSION: Although we could not replace 18F FDG PET-CT, MRI might be used as an adjunct to 18F FDG PET-CT for the evaluation of recurrent or cervical and upper mediastinal metastatic thyroid cancers; however, MRI is inadequate for the detection of metastases in small lymph nodes. PMID: 32008523 [PubMed - in process]
Source: Current Medical Imaging Reviews - Category: Radiology Tags: Curr Med Imaging Rev Source Type: research
Conclusions: The present study results show that all the dose parameters of HRCTV, bladder, and rectum with 60Co were comparable with those of 192Ir HDR source. The isodose distribution is more bulge out for 60Co in cranial-caudal direction compared to that of 192Ir. However, these differences can be reduced by treatment planning optimization techniques. The clinical plan evaluation in each slice and plane is necessary to explore the logistic and financial benefits of miniaturized 60Co source over 192Ir HDR source.
Source: Journal of Cancer Research and Therapeutics - Category: Cancer & Oncology Authors: Source Type: research
There are juxtaposed opinions in the literature as to the efficacy of fluorodeoxyglucose –positron emission tomography/computed tomography (FDG-PET/CT) for evaluating cervical lymph nodes in esophageal cancer. Much of this debate resides within a larger, more contentious issue–the potential treatment options for the cervical nodal basin. On one hand, 3-field dissection performed by experienced surgeons historically emerged as superior to lesser dissection. The vast experience of Akiyama and colleagues1 was described in their manuscript from 1994, in which patients treated with 3-field esophagectomy were found t...
Source: The Journal of Thoracic and Cardiovascular Surgery - Category: Cardiovascular & Thoracic Surgery Authors: Tags: Commentary Source Type: research
Accurate nodal staging is crucial for esophageal cancer. A prospective study was performed to assess the value of [18F] fluorodeoxyglucose (FDG) positron emission tomography (PET)/computed tomography (CT) for diagnosing cervical lymph node metastasis (LNM) of esophageal squamous cell carcinoma.
Source: The Journal of Thoracic and Cardiovascular Surgery - Category: Cardiovascular & Thoracic Surgery Authors: Tags: Thoracic Source Type: research
Accurate nodal staging is crucial for esophageal cancer. A prospective study was performed to assess the value of [18F] fluorodeoxyglucose (FDG) positron emission tomography (PET)/computed tomography (CT) for diagnosing cervical lymph node metastasis (LNM) of esophageal squamous cell carcinoma.
Source: The Journal of Thoracic and Cardiovascular Surgery - Category: Cardiovascular & Thoracic Surgery Authors: Source Type: research
In conclusion, the present case is an extremely rare occurrence of simultaneous multiple RDMs from PTC as the initial presentation.
Source: Frontiers in Endocrinology - Category: Endocrinology Source Type: research
ConclusionOur findings suggest that combination chemotherapy plus bevacizumab is an effective therapeutic option in patients with cutaneous lymphangitis carcinomatosa arising from cervical cancer.
Source: Journal of Medical Case Reports - Category: General Medicine Source Type: research
Conclusion: In papillary thyroid carcinoma I-131 post-ablation SPECT/CT scan detects cervical lymphadenopathy and predicts relapse by NM stage more accurately than WBS.
Source: In Vivo - Category: Research Authors: Tags: Clinical Studies Source Type: research
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