Danggui Buxue Tang ameliorates bleomycin-induced pulmonary fibrosis in rats through inhibiting transforming growth factor- β1/Smad3/ plasminogen activator inhibitor-1 signaling pathway.

CONCLUSION: Our findings suggest that DBT is able to ameliorate the pulmonary fibrosis, the possible mechanism may involve inhibition of pulmonary inflammation and collagen deposition, possibly via suppressing TGF-β1/Smad3/PAI-1 signaling pathway.
PMID: 32242389 [PubMed - in process]

Source: Journal of Traditional Chinese Medicine - March 31, 2020 Category: Complementary Medicine Authors: Wang J, Fang C, Wang S, Fang F, Chu X, Liu N, Lu C, Wang S, Li W, Fang C, Wang S Tags: J Tradit Chin Med Source Type: research