Validation of the Persian Work Productivity and Activity Impairment questionnaire in asthmatic patients.

Validation of the Persian Work Productivity and Activity Impairment questionnaire in asthmatic patients. Expert Rev Respir Med. 2020 Mar 31;: Authors: Seyedrezazadeh E, Ansarin K, Sharifi A, Jafari Rouhi AH, Gilani N, Aftabi Y, Khalili M, Najmi M Abstract Objective: The work productivity and activity impairment (WPAI) questionnaire is a fine linguistic validated tool to measure work productivity and activity impairment. Considering its capability, this study aimed to evaluate the validity of the Persian version of WPAI-AQ in asthmatics.Methods: The standard forward-backward process was used to translate the English version of WPAI-AQ into Persian. The convergent validity and responsiveness were evaluated by analysing the correlations between the Persian WPAI-AQ and the health outcomes, and its longitudinal change score with the change in SGRQ score, respectively. Additionally, the stability was estimated according to test-retest scores.Results: There was a significant correlation between the Persian WPAI-AQ related outcomes and symptoms, activities, and impacts of disease (r =0.41-0.89, p
Source: Expert Review of Respiratory Medicine - Category: Respiratory Medicine Tags: Expert Rev Respir Med Source Type: research

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CONCLUSIONS In this Caribbean population, uncontrolled asthma was independently associated with obesity, late-onset disease, and comorbidities of sleep apnea and depression. Poor asthma-related quality of life was independently associated with Indo-Caribbean ethnicity. PMID: 32493146 [PubMed - as supplied by publisher]
Source: Journal of Asthma - Category: Respiratory Medicine Tags: J Asthma Source Type: research
Conclusions: The scale successfully translated into BM and validated. The 10-item TAI-BM appears fit for use in testing inhaler adherence of Malaysian patients with asthma. PMID: 32493083 [PubMed - as supplied by publisher]
Source: Journal of Asthma - Category: Respiratory Medicine Tags: J Asthma Source Type: research
Authors: Brynjulfsen T, Demmelmaier I, Berntsen S, Foyn TH, Andersen OK, Stang J, Sigdestad JB, Stensrud T, Tufte K, Nielsen A, Westergren T Abstract We explored motivation for physical activity (PA) and exercise in adolescents with asthma who entered and continued a 10-week play-based exercise intervention. Eighteen adolescents with asthma, aged 13-17 years, participated in a 10-week play- and interval-based indoor exercise intervention during winter and autumn months. Semi-structured focus group interviews were conducted in weeks 2 and 8, focusing on motivation for PA and exercise, as well as field observations o...
Source: Journal of Asthma - Category: Respiratory Medicine Tags: J Asthma Source Type: research
Publication date: Available online 4 June 2020Source: International Journal of PharmaceuticsAuthor(s): Marwa Hasanein Asfour, Ahmed Alaa Kassem, Abeer Salama, Sameh Hosam Abd El-Alim
Source: International Journal of Pharmaceutics - Category: Drugs & Pharmacology Source Type: research
Publication date: Available online 4 June 2020Source: The Journal of Allergy and Clinical Immunology: In PracticeAuthor(s): Roberto Padoan, Fulvia Chieco Bianchi, Maria Rita Marchi, Diego Cazzador, Mara Felicetti, Enzo Emanuelli, Andrea Vianello, Piero Nicolai, Andrea Doria, Franco Schiavon
Source: The Journal of Allergy and Clinical Immunology: In Practice - Category: Allergy & Immunology Source Type: research
In this study, investigate whether there is an association between GSDMA (rs7212938, T/G) and GSDMB (rs7216389, T/C) at locus 17q21.2 and risk of Allergic Rhinitis among Jordanians. Also we aimed to determine if there is an association between such polymorphisms and the IgE level. METHODS: The study included 112 rhinitis patients and 111 Healthy controls. Gasdermin A (GSDMA) (rs7212938, T/G) and Gasdermin B (rs7216389, T/C) polymorphisms were genotyped using the PCR-RFLP method. RESULTS: On the genotype level, three analysis models were applied namely co-dominant, dominant and recessive genotypes. GSDMB CC genotype...
Source: Endocrine, Metabolic and Immune Disorders Drug Targets - Category: Drugs & Pharmacology Tags: Endocr Metab Immune Disord Drug Targets Source Type: research
Conditions:   COPD;   Asthma Intervention:   Diagnostic Test: Respimetrix flow-volume monitoring device Sponsor:   Pulmonary Critical Care Associates of Baltimore Not yet recruiting
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
Once-daily Enerzair® Breezhaler® (QVM149; IND/GLY/MF) met primary endpoint, demonstrating non-inferiority to a free combination of twice-daily Sal/Flu plus once-daily Tio in improving quality of life in people with uncontrolled asthma1 IND/GLY/M... Biopharmaceuticals, Drug Delivery Sosei Heptares, Novartis, Enerzair, Breezhaler, asthma
Source: HSMN NewsFeed - Category: Pharmaceuticals Source Type: news
Credit: u/USMCinUSABy Jan LundiusSTOCKHOLM / ROME, Jun 5 2020 (IPS) Another episode of the spectacular show that could be called The Greatest Story Ever Told: The Saga of the Trump Presidency, scripted and acted by Trump himself, took place on 1st of June. As U.S. cities were scenes of demonstrations and looting, President Trump declared himself to be ”the president of law and order” and said he was going to dispatch ”thousands and thousands” of law enforcement personell to Washington, to stop the ”destruction of property”. Meanwhile, tear gas, rubber bullets, shields and horses were us...
Source: IPS Inter Press Service - Health - Category: International Medicine & Public Health Authors: Tags: Crime & Justice Environment Featured Global Headlines Health Human Rights North America Religion TerraViva United Nations Water & Sanitation Source Type: news
Human neutrophil elastase (HNE) is a major cause of the destruction of tissues in cases of several different chronic andinflammatory diseases. Overexpression of the elastase enzyme plays a significant role in the pathogenesis of various diseases including chronic obstructive pulmonary disease (COPD), acute respiratory distress syndrome, rheumatoid arthritis, the rare disease cyclic hematopoiesis (or cyclic neutropenia), infections, sepsis, cystic fibrosis, myocardial ischemia/reperfusion injury and asthma, inflammation, and atherosclerosis. Human neutrophil elastase is secreted by human neutrophils due to different stimuli...
Source: Frontiers in Pharmacology - Category: Drugs & Pharmacology Source Type: research
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