Heart failure and diabetes, opportunities for improving treatment through patient characterization

Publication date: Available online 2 April 2020Source: Revista Clínica Española (English Edition)Author(s): J.P. Miramontes González, L. Pérez de Isla
Source: Revista Clinica Espanola - Category: Internal Medicine Source Type: research

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ConclusionPatients newly diagnosed with ATTRv amyloidosis have substantial healthcare utilization and costs in the first year, primarily the initial months, post-diagnosis. Further research should examine later costs associated with disease progression and end-of-life care.
Source: Neurology and Therapy - Category: Neurology Source Type: research
This article aims to review the key connections in the epidemiology and etiopathophysiology of type 2 diabetes and heart failure
Source: Clinics in Geriatric Medicine - Category: Geriatrics Authors: Source Type: research
AbstractType 2 diabetes mellitus (T2DM) is a known predisposing factor for heart failure (HF). The growing burden of these two conditions and their impact on health of the individual and on society in general needs urgent attention from the health care professionals. Availability of multiple treatment choices for managing T2DM and HF may make therapeutic decisions more complex for clinicians. Recent cardiovascular outcome trials of antidiabetic drugs have added very robust evidence to effectively manage subjects with this dual condition. This consensus statement provides the prevalence trends and the impact of this dual bu...
Source: Heart Failure Reviews - Category: Cardiology Source Type: research
ConclusionsOur findings suggest that empagliflozin prescribed for preventing CV death or hHF in T2DM patients seems to be cost saving compared to treatment with canagliflozin, and dapagliflozin.
Source: Clinical Drug Investigation - Category: Drugs & Pharmacology Source Type: research
Conclusion: The CareWell program resulted in improvements in the use of health services, strengthening the role of PC as the cornerstone of care provision for complex patients with multimorbidity. Published on 2020-05-22 11:47:30
Source: International Journal of Integrated Care - Category: Nursing Source Type: research
Conclusions. The key comorbidities that predict poorer 2-year survival outcomes after kidney transplantation have been identified in this large prospective cohort study. The findings will facilitate assessment of individual patient risks and evidence-based decision making.
Source: Transplantation - Category: Transplant Surgery Tags: Original Clinical Science—General Source Type: research
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Source: European Journal of Heart Failure - Category: Cardiology Authors: Tags: Review Source Type: research
AbstractThe heart failure (HF) epidemic is growing and approximately half of the HF patients have heart failure with preserved ejection fraction (HFpEF). HFpEF is a heterogeneous syndrome, characterized by a preserved left ventricular ejection fraction (LVEF ≥ 50%) with diastolic dysfunction, and is associated with high morbidity and mortality. Underlying comorbidities of HFpEF, i.e., hypertension, type 2 diabetes mellitus, obesity, and renal failure, lead to a systemic pro-inflammatory state, thereby affecting normal cardiac function. Increased inf lammatory biomarkers predict incident HFpEF and are higher in pa...
Source: Journal of Cardiovascular Translational Research - Category: Cardiology Source Type: research
This article is protected by copyright. All rights reserved.
Source: European Journal of Heart Failure - Category: Cardiology Authors: Tags: Review Source Type: research
Abstract Diabetes mellitus predisposes affected individuals to a significant spectrum of cardiovascular complications, one of the most debilitating in terms of prognosis is heart failure. Indeed, the increasing global prevalence of diabetes mellitus and an aging population has given rise to an epidemic of diabetes mellitus-induced heart failure. Despite the significant research attention this phenomenon, termed diabetic cardiomyopathy, has received over several decades, understanding of the full spectrum of potential contributing mechanisms, and their relative contribution to this heart failure phenotype in the sp...
Source: Circulation Research - Category: Cardiology Authors: Tags: Circ Res Source Type: research
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