Atopic Patients Who Fulfilled Rome III Criteria for Irritable Bowel Syndrome Had Higher Animal Danders Sensitization.

Atopic Patients Who Fulfilled Rome III Criteria for Irritable Bowel Syndrome Had Higher Animal Danders Sensitization. J Neurogastroenterol Motil. 2020 Apr 30;26(2):267-273 Authors: Siah KTH, Santosa A, Cheung CKY, Soh AYS, Bigliardi PL Abstract Background/Aims: The relationship between animal exposure and irritable bowel syndrome (IBS) is debated. Epidemiological studies have shown that atopy is more prevalent in IBS patients and vice versa. We set out to examine the association between animal danders sensitization and IBS-like symptoms in atopic patients. Methods: We recruited 69 consecutive atopic patients from the allergy clinic of a tertiary hospital. Subjects completed validated bowel questionnaires, underwent skin prick test, blood was collected for serum total immunoglobulin E, and ImmunoCAP immune solidphase allergen chip (ISAC) IgE multiplex assay. Results: Twenty-eight (41.0%) atopic patients fulfilled the Rome III IBS criteria (atopy-IBS). There were no differences in gender, age, pet ownership, total serum IgE, or food allergen sensitization between atopy-IBS group and atopy-non-IBS group. We found that atopy- IBS group had significantly higher number of positive skin prick test for cat dander (64.3% vs 24.4%, P
Source: Journal of Neurogastroenterology and Motility - Category: Gastroenterology Tags: J Neurogastroenterol Motil Source Type: research

Related Links:

Olivia posted this incredible story of wheat-free release in the comments on this blog some time back. Her story so powerfully encapsulates how far off course health can go by consuming this thing called “wheat,” that I thought it was worth sharing with everybody again. During her wheat-consuming days, Olivia was clearly suffering body-wide inflammation and other effects that were being ineffectively “treated” by her doctor, effects largely due to the indigestible or only partially-digestible proteins from the seeds of grasses AKA wheat. As often happens, she managed to reverse the entire collection...
Source: Wheat Belly Blog - Category: Cardiology Authors: Tags: Open gluten-free grain-free grains wheat belly Source Type: blogs
Abstract Non-celiac gluten sensitivity (NCGS) is a term that is used to describe individuals who are not affected by celiac disease or wheat allergy, yet they have intestinal and/or extra-intestinal symptoms related to gluten ingestion with improvement of their symptoms upon withdrawing gluten from their diet. Gluten-related disorder groups are manifested by symptoms of gastrointestinal tract disorders, as well as hematological dermatological endocrinological, gynecological, rheumatological and nervous system symptoms. It is believed that NCGS represents heterogeneous groups with different subgroups characterized ...
Source: Korean J Gastroenter... - Category: Gastroenterology Authors: Tags: Korean J Gastroenterol Source Type: research
Authors: Smith E, Foxx-Orenstein A, Marks LA, Agrwal N Abstract The nonpharmacologic management of irritable bowel syndrome focuses on dietary modification through the concept of food sensitivity or intolerance. Currently, testing for food allergies is not recommended in the absence of a clinical history consistent with an immunoglobulin E-mediated reaction. Objective means of determining food sensitivity, such as individualized diets, are being studied, but testing for food sensitivity is limited to certain food groups. Diets such as the low-FODMAPs (fermentable oligosaccharides, disaccharides, monosaccharides, an...
Source: Journal of the American Osteopathic Association - Category: Complementary Medicine Tags: J Am Osteopath Assoc Source Type: research
Conditions:   Irritable Bowel Syndrome With Constipation;   Functional Constipation Interventions:   Drug: Irritable Bowel Syndrome with Constipation (IBS-C) participants (LIN-MD-63 completers);   Drug: Functional Constipation (FC) participants (LIN-MD-62 and LIN-MD-64 completers): Sponsors:   Allergan;   Ironwood Pharmaceuticals, Inc. Not yet recruiting
Source: - Category: Research Source Type: clinical trials
We describe a patient with HAT and interstitial cystitis (IC) in whom bladder-directed therapy was effective in treating systemic symptoms.
Source: Annals of Allergy, Asthma and Immunology - Category: Allergy & Immunology Authors: Source Type: research
Purpose of review There is growing evidence encouraging the use of probiotics in many conditions in children. However, given the wide number of probiotics available and contradictory data in the literature, the health-care provider is often faced with uncertainness about whether or not to use probiotics and which one(s) to choose. We here review current hypotheses regarding the efficacy and safety of probiotics and evaluate the available data on the use of probiotics in most common diseases in children. Considering that probiotics have strain-specific effects, we will focus on individual probiotic strains rather than on ...
Source: Current Opinion in Pediatrics - Category: Pediatrics Tags: GASTROENTEROLOGY AND NUTRITION: Edited by Bradley Barth Source Type: research
Source: Gastroenterology - Category: Gastroenterology Authors: Source Type: research
Confocal laser endomicroscopy (CLE) is a technique that permits real-time detection and quantification of changes in intestinal tissues and cells, including increases in intraepithelial lymphocytes and fluid extravasation through epithelial leaks. Using CLE analysis of patients with irritable bowel syndrome (IBS), we found that more than half have responses to specific food components. Exclusion of the defined food led to long-term symptom relief. We used results of CLE to detect reactions to food in a larger patient population, and analyzed duodenal biopsies and fluid from patients to investigate mechanisms of these reactions.
Source: Gastroenterology - Category: Gastroenterology Authors: Source Type: research
This review explores possible etiologies for nonceliac gluten sensitivity, as well as the complex relationship between NCGS and irritable bowel syndrome.Current Opinion in Gastroenterology
Source: Medscape Allergy Headlines - Category: Allergy & Immunology Tags: Gastroenterology Journal Article Source Type: news
In this study, the gut microbiota of 30 LC patients and 30 healthy controls were examined via next-generation sequencing of 16S rRNA and analyzed for diversity and biomarkers. We found that there was no decrease in significant microbial diversity (alpha diversity) in LC patients compared to controls (P observed = 0.1422), while the composition (beta diversity) differed significantly between patients and controls (phylum [stress = 0.153], class [stress = 0.16], order [stress = 0.146], family [stress = 0.153]). Controls had a higher abundance of the bacterial phylum Actinobacteria and genus Bifidobacterium, while patients wi...
Source: Frontiers in cellular and infection microbiology - Category: Microbiology Source Type: research
More News: Allergy | Allergy & Immunology | Brain | Epidemiology | Gastroenterology | Irritable Bowel Syndrome | Neurology | Skin | Study