Detection, treatment and prevention of endodontic biofilm infections: what's new in 2020?

Detection, treatment and prevention of endodontic biofilm infections: what's new in 2020?
Crit Rev Microbiol. 2020 Apr 01;:1-19
Authors: Abusrewil S, Alshanta OA, Albashaireh K, Alqahtani S, Nile CJ, Scott JA, McLean W
Abstract
Endodontic disease, a biofilm infection of the root canal space, is a significant cause of dental morbidity worldwide. Endodontic treatment, or root canal treatment, as it is commonly known is founded on the ability to eradicate microbial biofilm infection and prevent re-infection of the highly complex root canal space. Despite many "advances" in clinical endodontics we have seen little improvement in outcomes. The aim of this critical review paper is to provide a contemporary view of endodontic microbiology and biofilm polymicrobiality, provide an understanding of the host response, and how together these impact upon clinical treatment. Ultimately, it is intended to provide insight into novel opportunities and strategies for the future diagnostics, treatment, and prevention of endodontic disease.
PMID: 32233822 [PubMed - as supplied by publisher]

Source: Critical Reviews in Microbiology - March 31, 2020 Category: Microbiology Authors: Abusrewil S, Alshanta OA, Albashaireh K, Alqahtani S, Nile CJ, Scott JA, McLean W Tags: Crit Rev Microbiol Source Type: research