Interstitial lung disease in primary immunodeficiency: towards a brighter future

Lung disease is a frequent clinical manifestation in people living with primary immunodeficiency diseases, the most prevalent of which are common variable immunodeficiency disorders (CVID). CVID is primarily characterised by antibody deficiency, but recent definitions and diagnostic criteria recognise a much more complex pattern of immunological defects [1]. CVID can be classified into two major clinical phenotypes. One group experiences infection as the only major clinical manifestation, whilst the other present a variety of lymphoproliferative, inflammatory and/or autoimmune complications.

Source: European Respiratory Journal - April 2, 2020 Category: Respiratory Medicine Authors: Hurst, J. R., Warnatz, K., on behalf of the ERS eGLILDnet Clinical Research Collaboration Tags: Editorials Source Type: research