Impact of depressive symptoms on self-perceived severity of autonomic dysfunction in multiple system atrophy: relevance for patient-reported outcomes in clinical trials

ConclusionsIn patients with MSA, depressive symptoms worsen the perceived severity of autonomic symptoms in general and orthostatic hypotension in particular. Our findings have implications for clinical trial design.

http://link.springer.com/10.1007/s10286-020-00681-6

Source: Clinical Autonomic Research - April 2, 2020 Category: Research Source Type: research