The impact of body weight on dysplasia of colonic adenomas: a case-control study.

CONCLUSIONS: Our findings support the protective effect a normal weight against advanced adenomas. Reduction of BMI value should be pursued in healthy programs. PMID: 32233893 [PubMed - as supplied by publisher]
Source: Scandinavian Journal of Gastroenterology - Category: Gastroenterology Tags: Scand J Gastroenterol Source Type: research

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Prediabetes is associated with a high risk of colon cancer, and abdominal obesity, which can result in the secretion of several obesity-related adipocytokines, is an independent influencing factor for colonic ...
Source: BMC Endocrine Disorders - Category: Endocrinology Authors: Tags: Research article Source Type: research
ConclusionOur results suggest that obesity might be an initiator for colon adenomas but not a promoter for colorectal cancer among Black women.
Source: Cancer Causes and Control - Category: Cancer & Oncology Source Type: research
Publication date: Available online 28 December 2019Source: Biochimica et Biophysica Acta (BBA) - Molecular Basis of DiseaseAuthor(s): Snahlata Singh, Shyamananda Singh Mayengbam, Surbhi Chouhan, Bhavana Deshmukh, Pranay Ramteke, Dipti Athavale, Manoj Kumar BhatAbstractEpidemiological studies over the last few decades have shown a strong influence of obesity on colon cancer risk and its progression. These studies have primarily focussed on the role of adipokines in driving cancer progression. We investigated the incidence of cancerous polyp formation and tumor progression in presence and absence of functional leptin along w...
Source: Biochimica et Biophysica Acta (BBA) Molecular Basis of Disease - Category: Molecular Biology Source Type: research
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Source: Journal of Taibah University Medical Sciences - Category: Universities & Medical Training Source Type: research
ConclusionOur data suggest that RYGB is associated with an increased risk of serrated polyps after 5  years from surgery. Prospective studies defining this risk and examining mechanisms will be instrumental for application of CRC preventative strategies in this population.
Source: Obesity Surgery - Category: Surgery Source Type: research
AbstractThere are known short-term benefits in breastfed infants versus bottle-fed infants in terms of lower risks of infection and obesity in infancy and childhood, but the long-term effect on the risk of adult cancers is unclear. In a cohort of 1 in 4 UK women born in 1935 –1950 we report the incidence of adult cancers in relation to having been breastfed in infancy. In median year 2001 (interquartile range 2000–2003) 548,741 women without prior cancer reported whether they had been breastfed. There was 81% agreement between women’s report of having been breastf ed and information on breastfeeding recor...
Source: European Journal of Epidemiology - Category: Epidemiology Source Type: research
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Source: Surgery - Category: Surgery Authors: Source Type: research
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Source: Frontiers in Immunology - Category: Allergy & Immunology Source Type: research
(Bentham Science Publishers) Recent epidemiological and experimental studies have shown that obesity is a major risk factor for Colorectal Cancer (CRC). Regular intake of high fat-containing diet can promote obesity and metabolic syndrome by increasing the insulin resistance and inflammatory response which contribute to carcinogenesis.
Source: EurekAlert! - Cancer - Category: Cancer & Oncology Source Type: news
This study analyzed data from women over 40 and compared the size of breast cancers at the time of diagnosis detected in the 1970s (before mammography became common) with the size of tumors detected between 2000 and 2002, when screening mammography was routine. Treatments and rates of death due to breast cancer 10 years after the diagnosis were also analyzed. The study found that: As more women underwent routine screening mammograms, more small breast cancers were detected. Many of these tumors were restricted to the ducts within the breast (called ductal carcinoma in situ), and even without treatment would never threaten...
Source: Harvard Health Blog - Category: Consumer Health News Authors: Tags: Health Source Type: blogs
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