Perinatal photoperiod and childhood cancer: pooled results from 182,856 individuals in the international childhood cancer cohort consortium (I4C).

In conclusion, in this first study of perinatal photoperiod and childhood cancer, we detected an inverse ["protective"] linear association between third trimester mean daily photoperiod and childhood cancer risk in the 8-16-h set of the total study population. Limited statistical power impeded the investigation of risks with individuals exposed to more extreme photoperiods. Future studies are needed to confirm differential photoperiod-associated risks and further investigations into the hypothesized circadian imprinting mechanism are warranted.
PMID: 32233647 [PubMed - as supplied by publisher]

Source: Chronobiology International - March 31, 2020 Category: Biology Authors: Lewis P, Hellmich M, Fritschi L, Tikellis G, Morfeld P, Groß JV, Foster RG, Paltiel O, Klebanoff MA, Golding J, Olsen S, Magnus P, Ponsonby AL, Linet MS, Ward MH, Caporaso N, Dwyer T, Erren TC Tags: Chronobiol Int Source Type: research