Efficacy of Intravenous Hydroxocobalamin for Treatment of Sodium Methanethiolate Exposure in a Swine Model (Sus scrofa) of Severe Methanethiol Toxicity.

CONCLUSIONS: In our model of intravenous methanethiolate poisoning, IV HOC administration resulted in a transient improvement in vital signs and prolonged time to death; however, it did not improve survival. PMID: 32239422 [PubMed - as supplied by publisher]

https://www.ncbi.nlm.nih.gov/pubmed/32239422?dopt=Abstract

Source: Journal of Medical Toxicology - March 31, 2020 Category: Toxicology Authors: Maddry JK, Paredes RM, Rebeles J, Olson G, Castaneda M, Canellis K, Ng PC, Bebarta VS Tags: J Med Toxicol Source Type: research