Lower extremity peripheral artery disease: a basic approach.
Lower extremity peripheral artery disease: a basic approach. Br J Hosp Med (Lond). 2020 Mar 02;81(3):1-9 Authors: Chan KA, Junia A Abstract Peripheral artery disease of the lower limbs is a chronically progressive disorder characterised by the presence of occlusive lesions in the medium and large arteries that result in symptoms secondary to insufficient blood flow to the lower extremities. It is both a manifestation of systemic atherosclerosis and a marker of increased cardiovascular morbidity and mortality. Because of its highly heterogenous clinical picture, a detailed history and physical assessment, a high degree of suspicion for peripheral artery disease and the use of the ankle-brachial pressure index is essential to identify patients with peripheral artery disease. This will allow early administration of basic pharmacotherapy and lifestyle changes to reduce cardiovascular events, minimise claudication symptoms and enable optimal revascularisation to prevent loss of limb function. PMID: 32240007 [PubMed - as supplied by publisher]
Abstract Peripheral artery disease is a common disorder and a major cause of morbidity and mortality worldwide. Therapy is directed at reducing the risk of major adverse cardiovascular events and at ameliorating symptoms. Medical therapy is effective at reducing the incidence of myocardial infarction and stroke to which these patients are prone but is inadequate in relieving limb-related symptoms, such as intermittent claudication, rest pain, and ischemic ulceration. Limb-related morbidity is best addressed with surgical and endovascular interventions that restore perfusion. Current medical therapies have only mod...
Abstract OBJECTIVE: The aims of this study were firstly to assess the correlation between disease specific measures of quality of life (QOL) and physical performance and activity, and secondly to identify demographic, clinical, functional, and physical activity measures independently associated with QOL in people with intermittent claudication. METHODS: This was a cross sectional observational study of 198 people with intermittent claudication caused by peripheral artery disease who were recruited prospectively. QOL was assessed with the intermittent claudication questionnaire (ICQ) and the eight-theme periph...
The aims of this study were firstly to assess the correlation between disease specific measures of quality of life (QOL) and physical performance and activity, and secondly to identify demographic, clinical, functional, and physical activity measures independently associated with QOL in people with intermittent claudication.
Prospective study of the Patient-Centered Outcomes Related to Treatment Practice in Peripheral Vascular Disease: Investigating Trajectories (PORTRAIT) registry from 16 vascular specialty clinics (United States, 10; The Netherlands, 5; Australia, 1) between 2011 and 2015.
Peripheral artery disease (PAD) has been shown to affect health status and quality of life, however, the disability associated by specific anatomic level of disease is unknown. We evaluated patients presenting with claudication by anatomic level and utilized the Peripheral Artery Questionnaire (PAQ), a PAD-specific validated tool, to quantify patients' symptoms, function, treatment satisfaction, and quality of life.
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Conclusion: In this small exploratory study, HTPR was frequent in PAD patients. Furthermore, the results are suggestive that MALE might be associated with dual HTPR. This leads to the hypothesis that optimized antithrombotic regimens post percutaneous transluminal angioplasty should be tested in clinical trials. PMID: 32252582 [PubMed - as supplied by publisher]
Patients with peripheral artery disease and associated intermittent claudication can experience significant short-term (for instance, day-to-day) variations in their walking ability. This variability is often viewed as a complication in establishing reliable baseline walking performance levels for individual patients in multi-patient supervised walking programs.
Hernandez et al.1 have recently published a study that aimed to characterize physical activity and sedentary behavior in patients with peripheral artery disease (PAD) and intermittent claudication. Although interesting, their article contains incorrect information and questionable data analysis and interpretation.
The aims of this investigation were to determine whether the daily dietary intake of nutrients by patients with peripheral artery disease (PAD) and intermittent claudication (IC) met recommended levels for adults older than 50 years and to determine whether meeting recommended levels of nutrients was associated with ankle-brachial index (ABI), inflammation, and ambulation of patients with PAD and IC.