Male patients with unilateral breast symptoms: an optimal imaging approach

AbstractObjectivesTo evaluate the usefulness of bilateral mammography in male patients with unilateral breast symptoms, including investigation of the diagnostic performance of unilateral and bilateral reviews and the average glandular dose (AGD) per exposure.MethodsTwo hundred seventy-one consecutive male patients (mean age, 57  years) with unilateral breast symptoms underwent bilateral mammography. Image interpretation was performed in two ways, first with a unilateral review of the symptomatic breast and then with a bilateral review. A modified BI-RADS scale (from 1 to 5) was used. The diagnostic performance of unilater al and bilateral reviews was compared, and contralateral breast abnormalities and the AGD per exposure were recorded. We also analyzed ultrasound (US) results and compared them with mammography.ResultsOf 271 male patients, 29 were pathologically diagnosed with breast cancer. There was no bilateral breast cancer. The sensitivity, specificity, positive and negative predictive values, and accuracy were 96.6%, 96.7%, 77.8%, 99.6%, and 96.7%, respectively, for unilateral review, and 96.6%, 95.9%, 73.7%, 99.6%, and 95.9% for bilateral review. Receiver operator characteristic analysis showed excellent diagnostic performance for both methods: the area under the curve (AUC) was 0.966 for unilateral review and 0.962 for bilateral review (p = 0.415). The mean AGD per exposure was 1.10 ± 0.29 mGy for symptomatic breast and 1...
Source: European Radiology - Category: Radiology Source Type: research

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A 60-year-old woman with no known family history of breast cancer and an unremarkable medical history presented to her primary care physician after self-palpating a mass in her left breast. A mammogram and ultrasound demonstrated a 3.5 × 3.4-cm mass at 7 o’clock, 5 cm from the nipple in her left breast. A biopsy showed infiltrating, moderately differentiated mammary carcinoma with ductal and lobular features. Estrogen and progesterone receptors stained positive, human epidermal growth factor receptor-2 was negative by immunohis tochemistry, and Ki67 was>50%.
Source: International Journal of Radiation Oncology * Biology * Physics - Category: Radiology Authors: Tags: Gray Zone Source Type: research
We present a rare case of Paget disease of the nipple without the typical characteristics, detected by simple nipple scraping technique. A 62-year-old woman presented with a small fissure on the left nipple with scant clear nippledischarge. There were no other changes to the nipple-areola complex. The mammography and ultrasound were unremarkable. However, nipplescraping provided the immediate cytological diagnosis of Paget disease. Breast MRI with core biopsy showed high grade ductal carcinoma in situwith suggestion of microinvasion, confirmed histologically after mastectomy. Nipple scraping is a simple and inexpensive tec...
Source: Dermatology Online Journal - Category: Dermatology Source Type: research
AbstractBackgroundBreast density is an independent risk factor for breast cancer. Mammography is supplemented with handheld ultrasound (HHUS) to increase sensitivity. Automatic breast ultrasound (ABUS) is an alternative to HHUS. Our study wanted to assess the difference in execution and reading time between ABUS and HHUS.Methods and materialsN = 221 women were evaluated consecutively between January 2019 and June 2019 (average age 53 years; range 24–89). The execution and reading time of ABUS and HHUS was calculated with an available stopwatch. Time started for both procedures when the patient was ...
Source: La Radiologia Medica - Category: Radiology Source Type: research
Abstract A 54-year-old woman on methotrexate (MTX) treatment developed reddish skin change in her right breast. Mammography and ultrasound showed no masses in the breasts but bilateral mammary glands presented diffuse lower-level echoes. Only 19 days later, the patient developed bilateral breast masses. Histological examination showed that diffuse large B-cell lymphoma cells spread widely and sparsely in the bilateral breasts in addition to the tumor cell conglomerate, leading to the diagnosis of MTX-associated lympho-proliferative disorders (MTX-LPDs). Withdrawal of MTX resulted in complete disappearance of ...
Source: Breast Cancer - Category: Cancer & Oncology Authors: Tags: Breast Cancer Source Type: research
Like everyone, I assume I’ll live forever. Although I often wonder whether anyone would come to my funeral and who would wear black, it never actually occurrs to me that there is an endpoint. It’s almost as if I would come along too to watch proceedings running smoothly and along the lines I wanted. Death was something I thought about, but in a rather abstract, offhand sort of way. It happened, of course I knew I would die at some point, but that point was somewhere out there … way off from here, where I am now. And then I hit a brick wall. The wall consisted of a tiny little bit of blood coughed up in s...
Source: The Hysterectomy Association - Category: OBGYN Authors: Tags: Emotional Health Happiness Thought for the day Women's Health my story Source Type: news
Jacinta E. Browne The aim of this work was to develop multimodal anthropomorphic breast phantoms suitable for evaluating the imaging performance of a recently-introduced Microwave Imaging (MWI) technique in comparison to the established diagnostic imaging modalities of Magnetic Resonance Imaging (MRI), Ultrasound (US), mammography and Computed Tomography (CT). MWI is an emerging technique with significant potential to supplement established imaging techniques to improve diagnostic confidence for breast cancer detection. To date, numerical simulations have been used to assess the different MWI scanning and image recon...
Source: Sensors - Category: Biotechnology Authors: Tags: Article Source Type: research
This article focuses on reviewing the background of microwave techniques for breast tumour detection. In particular, this study reviews the recent advancements in active microwave imaging, namely microwave tomography and radar-based techniques. The main objective of this paper is to provide researchers and physicians with an overview of the principles, techniques, and fundamental challenges associated with microwave imaging for breast cancer detection. Furthermore, this study aims to shed light on the fact that until today, there are very few commercially available and cost-effective microwave-based systems for breast canc...
Source: Sensors - Category: Biotechnology Authors: Tags: Review Source Type: research
Eight recommendations released for imaging women post-mastectomy and breast reconstruction.
Source: Diagnostic Imaging - Category: Radiology Authors: Tags: Breast Health Ultrasound Breast Imaging Mammography Screening Tomosynthesis Source Type: news
Abstract Detection of breast cancer has particular importance for the diagnosis of cancer diseases. This is the most common type of cancer among women. Breast cancer is a malignant tumor of the glandular tissue of the breast. It is proposed to use infrared spectroscopy of blood serum as a simple and quick way to detect breast cancer. The paper presents the results of research using the methods of multivariate processing of IR spectra of human blood serum obtained by ATR-FTIR spectroscopy. The paper presents the results of research using the methods of multivariate processing of IR spectra of human blood serum obta...
Source: Talanta - Category: Chemistry Authors: Tags: Talanta Source Type: research
AbstractIntroductionBreast cancer is the most commonly diagnosed female cancer. Diagnosis in younger women (under 35  years) is different to their older counterparts, and mammography is not considered as sensitive in this cohort. Consequentially, younger patients may present later with more advanced disease.MethodsThis is a retrospective analysis of a prospectively updated database containing consecutive patients who presented to the symptomatic breast unit of Galway University Hospital between 2009 and 2015. Patient clinicopathologic factors, clinical examination features, diagnostic radiological modalities and Bi-RA...
Source: Irish Journal of Medical Science - Category: General Medicine Source Type: research
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