Contribution of Splenic Resistance Arteries to Splanchnic Blood Overflow in Cirrhosis

ConclusionIn cirrhotic rats, a decreased splenic arterial response to vasoconstrictors, rather than an increased response to vasodilators, contributes to splanchnic vasodilation, while in mesenteric arteries also an increased response to vasodilators secondary to, but not only, eNOS and iNOS overexpression, plays a role.

http://link.springer.com/10.1007/s10620-020-06233-2

Source: Digestive Diseases and Sciences - April 1, 2020 Category: Gastroenterology Source Type: research