Cancers, Vol. 12, Pages 863: Mass Spectrometry Imaging Reveals Neutrophil Defensins as Additional Biomarkers for Anti-PD-(L)1 Immunotherapy Response in NSCLC Patients

Conclusions: With proteomic approaches, we have discovered neutrophil defensins as additional prospective biomarkers for an anti-PD-(L)1 immunotherapy response. Thereby, we also demonstrated that the neutrophil defensins contribute in the activation of the immune response towards cancer cells, which could provide a new lead towards an anticancer therapy.

Source: Cancers - April 1, 2020 Category: Cancer & Oncology Authors: Eline Berghmans Julie Jacobs Christophe Deben Christophe Hermans Glenn Broeckx Evelien Smits Evelyne Maes Jo Raskin Patrick Pauwels Geert Baggerman Tags: Article Source Type: research