Nonfatal Drug Overdoses Treated in Emergency Departments - United States, 2016-2017

In the United States, rates of nonfatal overdose visits to emergency departments increased from 2016 to 2017 for all drugs (4.3%), all opioids (3.1%), nonheroin opioids (3.6%), heroin (3.6%), and cocaine (32.9%), while rates of overdoses involving benzodiazepines decreased (5.2%).
Source: CDC Morbidity and Mortality Weekly Report - Category: American Health Tags: MMWR Morbidity & Mortality Weekly Report Overdose Opioids Source Type: news

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Purpose of review The aim of this review is to provide an update on recent trends of New Psychoactive Substances (NPS) and the current global strategies implemented to manage them. Recent findings The number of NPS has increased from 166 in 2009 to 892 in 2018, with about 36% having stimulant effects. Such trend revels some unprecedented patterns. The decline in the emergence of new synthetic cannabinoids has coincided with rising deaths due to overdose of fentanyl and non-fentanyl compounds in North America and Europe. The detection of new stimulant NPS has stabilized since 2015. Although the level of seizures of mep...
Source: Current Opinion in Psychiatry - Category: Psychiatry Tags: ADDICTIVE DISORDERS: Edited by John B. Saunders and Linda B. Cottler Source Type: research
BACKGROUND: There have been significant efforts to respond to the two public health emergencies of coronavirus disease 2019 (COVID-19) and overdose in British Columbia (BC), Canada. The purpose of this study was to quantify the prevalence of known risk fac...
Source: SafetyLit - Category: International Medicine & Public Health Tags: Alcohol and Other Drugs Source Type: news
BACKGROUND: From 1999 to 2017, more than 400,000 Americans died from a drug overdose death involving an opioid. Early surveillance studies have observed large variations in opioid-involved overdose deaths among different geographic regions and racial/ethni...
Source: SafetyLit - Category: International Medicine & Public Health Tags: Alcohol and Other Drugs Source Type: news
Fewer than 20 percent of people with private healthcare insurance who suffered a non-fatal opioid overdose ultimately receive abuse or addiction treatment, according to a study published Wednesday by JAMA Network Open.
Source: Health News - - Category: Consumer Health News Source Type: news
(Bentham Science Publishers) In the past two decades more than 700,000 people have died from a drug overdose in the United States. In 2017, more than 68% of the drug overdose deaths involved an opioid. To help stem this epidemic, Highmark Inc. developed, implemented and evaluated a series of quality management-focused opioid interventions utilizing a three-pronged public health approach.
Source: EurekAlert! - Medicine and Health - Category: International Medicine & Public Health Source Type: news
(National Institute for Health and Welfare) Despite the fact that the Nordic countries are often seen as ideal in practically every global ranking of quality of life and social equality, the number of drug-related deaths in these countries are among the highest in Europe.
Source: EurekAlert! - Social and Behavioral Science - Category: International Medicine & Public Health Source Type: news
(University of Pennsylvania School of Medicine) The majority of commercially insured patients who visited the emergency department (ED) for an opioid overdose didn't receive the timely follow-up care known to help prevent a future overdose or death. Of nearly 6,500 patients treated in EDs nationwide for an overdose or other opioid-related medical complications, only 16 percent accessed opioid use disorder (OUD) medications or another form of treatment within three months of the ED visit
Source: EurekAlert! - Social and Behavioral Science - Category: International Medicine & Public Health Source Type: news
Source: Clinical Toxicology - Category: Toxicology Authors: Source Type: research
AbstractAmidst the opioid overdose crisis, there are increased efforts to expand access to medications for opioid use disorder (MOUD). Hospitalization for the complications of substance use in the United States (US) provides an opportunity to initiate methadone, buprenorphine, and extended release naltrexone and link high-risk, not otherwise engaged, patients into outpatient care. However, treatment options for patients are quickly exhausted when these medications are not desired, tolerated, or beneficial. As an example, we discuss the case of a man who was hospitalized 27 times over 2  years for complications related...
Source: Journal of General Internal Medicine - Category: Internal Medicine Source Type: research
Abstract Previous studies suggest that genistein protects liver from acetaminophen (APAP)-induced injury, however, the detailed mechanism of the process is still incompletely. Therefore, present study was to investigate the potential mechanism of the genistein mediated protection against APAP-induced hepatotoxicity. As shown, supplementation with 150 mg/kg genistein greatly alleviated the increase in serum alanine aminotransferase (ALT) activity, aspartate aminotransferase (AST) activity, hepatic malondialdehyde (MDA) contents, and reversed the decrease in hepatic GSH levels in response to overdose APAP. At t...
Source: Biochemical and Biophysical Research communications - Category: Biochemistry Authors: Tags: Biochem Biophys Res Commun Source Type: research
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