Genotyping Array Design and Data Quality Control in the Million Veteran Program

The Million Veteran Program (MVP), initiated by the Department of Veterans Affairs (VA), aims to collect biosamples with consent from at least one million veterans. Presently, blood samples have been collected from over 800,000 enrolled participants. The size and diversity of the MVP cohort, as well as the availability of extensive VA electronic health records, make it a promising resource for precision medicine. MVP is conducting array-based genotyping to provide a genome-wide scan of the entire cohort, in parallel with whole-genome sequencing, methylation, and other ‘omics assays.

Source: The American Journal of Human Genetics - April 1, 2020 Category: Genetics & Stem Cells Authors: Haley Hunter-Zinck, Yunling Shi, Man Li, Bryan R. Gorman, Sun-Gou Ji, Ning Sun, Teresa Webster, Andrew Liem, Paul Hsieh, Poornima Devineni, Purushotham Karnam, Xin Gong, Lakshmi Radhakrishnan, Jeanette Schmidt, Themistocles L. Assimes, Jie Huang, Cuiping Tags: Article Source Type: research